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ChemicalBook >> CAS DataBase List >>1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone

1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone

1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone Structure
1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone structure
CAS No.
358780-14-0
Chemical Name:
1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone
Synonyms
1-(6-(Trifluoromethyl);1-(6-(Trifluoromethyl)pyridin-3-yl);5-Acetyl-2-(trifluoromethyl)pyridine;5-Acetyl-2-(trifluoromethyl)pyridine 97+%;[6-(TRIFLUOROMETHYL)PYRIDIN-3-YL]ETHANONE;1-[6-(Trifluoromethyl)-3-pyridyl]ethanone;1-[6-(TRIFLUOROMETHYL)PYRIDIN-3-YL]ETHANONE;1-(6-(trifluoroMethyl)pyridine-3-yl)ethanone;1-(6-(trifluoromethyl)pyridin-3-yl) ethenone;1-[6-(Trifluoromethyl)pyridin-3-yl]ethan-1-one
CBNumber:
CB6845081
Molecular Formula:
C8H6F3NO
Molecular Weight:
189.13
MDL Number:
MFCD07375085
MOL File:
358780-14-0.mol
Last updated:2024-04-03 17:07:09
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1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone Properties

Boiling point 233.7±40.0 °C(Predicted)
Density 1.280±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka -1.24±0.22(Predicted)
InChI InChI=1S/C8H6F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-4H,1H3
InChIKey NAUKVLRFGMDIAN-UHFFFAOYSA-N
SMILES C(=O)(C1=CC=C(C(F)(F)F)N=C1)C

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335-H302
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P
HS Code  2933399990

1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T899335 1-(6-(trifluoromethyl)pyridin-3-yl)ethanone 358780-14-0 500mg $310 2021-12-16 Buy
Apolloscientific PC5837 5-Acetyl-2-(trifluoromethyl)pyridine 97+% 358780-14-0 5g $439 2021-12-16 Buy
Apolloscientific PC5837 5-Acetyl-2-(trifluoromethyl)pyridine 97+% 358780-14-0 250mg $59 2021-12-16 Buy
SynQuest Laboratories 4H17-3-Y4 5-Acetyl-2-(trifluoromethyl)pyridine 97.0% 358780-14-0 250mg $95 2021-12-16 Buy
SynQuest Laboratories 4H17-3-Y4 5-Acetyl-2-(trifluoromethyl)pyridine 97.0% 358780-14-0 1g $236 2021-12-16 Buy
Product number Packaging Price Buy
T899335 500mg $310 Buy
PC5837 5g $439 Buy
PC5837 250mg $59 Buy
4H17-3-Y4 250mg $95 Buy
4H17-3-Y4 1g $236 Buy

1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone Chemical Properties,Uses,Production

Uses

1-(6-(Trifluoromethyl)pyridin-3-yl)ethanone can be used as novel GPR119 agonists.

Synthesis

To a solution of 2-trifluoromethyl-5-bromopyridine (5.0 g, 22 mmol) in Et2O (50 mL) was added sec-BuLi (0.91 M in cyclohexane, 24 mL, 22 mmol) at -78 °C. After 10 minutes of stirring, N,N-dimethylaminoacetamide (2.3 mL, 24 mmol) dissolved in Et2O (10 mL) was added drop wise. Stirring was continued at -78 °C for 1 h and then at rt over night. The reaction mixture was poured into water (100 mL) and the water phase was extracted with Et2O (3×100 mL). Combined organics were washed with water and brine and dried (MgSO4). After careful evaporation of the solvent, the crude was purified by column chromotography (SiO2, pentane/ether 9/1) to give 1-(6-(Trifluoromethyl)pyridin-3-yl)ethanone (2.3 g, 12 mmol, 54%) as a light yellow solid. 1H NMR (CDCl3) δ 9.26 (br s, 1H) 8.43 (br d, J=5.6 Hz, 1H) 7.83 (br d, J=7.2 Hz, 1H) 2.71 (s, 3H).
1-(6-(Trifluoromethyl)pyridin-3-yl)ethanone synthesis

1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone synthesis

358780-13-9
108-59-8
358780-14-0
Synthesis of 1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone from 6-(TRIFLUOROMETHYL)NICOTINOYL CHLORIDE and Dimethyl malonate

1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine

1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone Suppliers

Global( 109)Suppliers
Supplier Tel Email Country ProdList Advantage
Zhengzhou Anbu Chem Co.,Ltd 		+86-0371-88006763; +8615988602810 sales@anbuchem.com China 3000 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7845 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Tianjin Huiren Chemtech Co., Ltd 		+86-86-22-23707858 +86-86-13672008665 huirentech@foxmail.com China 169 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49390 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Allfluoro pharmaceutical co. ltd. 		021-26137118 +8615821363818 sales@allfluoro.com China 5791 58
WinWin Chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 13854 58
Blocksynth Pharmaceutical Technology Co.,Ltd 		0086-19817745290; +8619817745290 bd@blocksynth.com China 5658 58
Supplier Advantage
Zhengzhou Anbu Chem Co.,Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
ATK CHEMICAL COMPANY LIMITED 		60
Tianjin Huiren Chemtech Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Allfluoro pharmaceutical co. ltd. 		58
WinWin Chemical CO., Limited 		58
Blocksynth Pharmaceutical Technology Co.,Ltd 		58

View Lastest Price from 1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone pictures 2024-04-03 1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone
358780-14-0
 US $20.00-0.60 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
1-[6-(TRIFLUOROMETHYL)PYRIDIN-3-YL]ETHANONE pictures 2023-06-14 1-[6-(TRIFLUOROMETHYL)PYRIDIN-3-YL]ETHANONE
358780-14-0
 US $0.00 / KG 0.1KG 99% 1000KGS Zhengzhou Anbu Chem Co.,Ltd
1-[6-(TRIFLUOROMETHYL)PYRIDIN-3-YL]ETHANONE pictures 2023-04-15 1-[6-(TRIFLUOROMETHYL)PYRIDIN-3-YL]ETHANONE
358780-14-0
 US $0.00 / KG 0.1KG 98% 1000KGS Zhengzhou Anbu Chem Co.,Ltd

358780-14-0(1-(6-(trifluoroMethyl)pyridin-3-yl)ethanone)Related Search:

N-BENZYL-5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE N-METHOXY-N-METHYL-N'-[5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDIN-3-YL]UREA N-(2,6-DIMETHYLPHENYL)-5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE N-(2,4-DIFLUOROPHENYL)-5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE 5-OXO-2-(TRIFLUOROMETHYL)-N-[3-(TRIFLUOROMETHYL)BENZYL]-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE
S-ETHYL N-[5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDIN-3-YL]CARBAMOTHIOATE 5-OXO-N-(3-PYRIDINYLMETHYL)-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE METHYL N-[5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDIN-3-YL]CARBAMATE N,N-DIMETHYL-N'-[5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDIN-3-YL]UREA N-(4-CHLOROBENZYL)-5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE
N-METHYL-5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE N-ISOPROPYL-5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE 5-OXO-2-(TRIFLUOROMETHYL)-N-[3-(TRIFLUOROMETHYL)PHENYL]-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE 5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID N-ALLYL-5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE
N-(4-CHLOROPHENYL)-5-OXO-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE 5-OXO-N-PHENYL-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE 5-OXO-N-(2-PYRIDINYLMETHYL)-2-(TRIFLUOROMETHYL)-5H-CHROMENO[2,3-B]PYRIDINE-3-CARBOXAMIDE

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5-Acetyl-2-(trifluoromethyl)pyridine 1-(6-(trifluoroMethyl)pyridine-3-yl)ethanone [6-(TRIFLUOROMETHYL)PYRIDIN-3-YL]ETHANONE 1-(6-(Trifluoromethyl) 1-(6-(Trifluoromethyl)pyridin-3-yl) 1-[6-(TRIFLUOROMETHYL)PYRIDIN-3-YL]ETHANONE ETHANONE, 1-[6-(TRIFLUOROMETHYL)-3-PYRIDINYL]- 1-[6-(Trifluoromethyl)pyridin-3-yl]ethan-1-one 5-Acetyl-2-(trifluoromethyl)pyridine 97+% 1-（6-(trifluoromethyl) -3-pyridine ） ethyl ketone 1-(6-(trifluoromethyl)pyridin-3-yl) ethenone 1-[6-(Trifluoromethyl)-3-pyridyl]ethanone 358780-14-0