Regramostim
- CAS No.
- 127757-91-9
- Chemical Name:
- Regramostim
- Synonyms
- CSF-2;MGI-1GM;Regramostim;Regramostime;Regramostimum;pluripoietin-;pluripoietin-a;GM-CSF from mouse;Regramostimum [inn-latin];Regramostime [inn-french]
- CBNumber:
- CB71105992
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| storage temp. | -20°C |
|---|---|
| form | lyophilized |
| color | white to off-white |
| FDA UNII | KR89Q40F01 |
Regramostim price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP3201 | GM-CSF from mouse Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 127757-91-9 | 20μG | $419 | 2023-06-20 | Buy |
| Biorbyt Ltd | orb529070 | CSF2 | 127757-91-9 | 10μg | $287.3 | 2021-12-16 | Buy |
Regramostim Chemical Properties,Uses,Production
Uses
Antineutropenic; hematopoietic stimulant.
Uses
GM-CSF (granulocyte-macrophage colony-stimulating factor) mouse has been used to check effect of GM-CSF on retinal ganglion cell neurite outgrowth in the retinal explants.
General Description
GM-CSF (granulocyte-macrophage colony-stimulating factor, also referred to as CSF2) is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. Recombinant murine GM-CSF is a 14.2kDa globular protein consisting of 124 amino acids residues. The human and murine molecules are species-specific and exhibit no cross-species reactivity.
Biochem/physiol Actions
GM-CSF (granulocyte-macrophage colony-stimulating factor, also referred to as CSF2) is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It enhances neutrophil migration. GM-CSF plays a crucial role in inflammatory and autoimmune diseases. In neutrophils, it promotes the expression of TLR2 (Toll-like receptor) and TLR2-associated interleukin 8 responses, thereby eliminating microbial attack.
Regramostim Preparation Products And Raw materials
Raw materials
Preparation Products
Regramostim Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Nanjing Leon Biological Technology Co., Ltd. | 17705183659 | sales@njleonbiotech.com | China | 5503 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-025-58361106-805-805 13082558573 | liugang@njpeptide.com | China | 9962 | 55 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19105 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |