ChemicalBook >> CAS DataBase List >>O-desmethyl Brinzolamide (hydrochloride)
O-desmethyl Brinzolamide (hydrochloride)
- CAS No.
- 2967475-56-3
- Chemical Name:
- O-desmethyl Brinzolamide (hydrochloride)
- Synonyms
- O-desmethyl Brinzolamide (hydrochloride)
- CBNumber:
- CB713741805
- Molecular Formula:
- C11H19N3O5S3.ClH
- Molecular Weight:
- 405.95
- MDL Number:
- MOL File:
- 2967475-56-3.mol
Last updated:2025-04-18 09:52:37
O-desmethyl Brinzolamide (hydrochloride) Chemical Properties,Uses,Production
Uses
O-Desmethyl Brinzolamide hydrochloride (compound 6a), an active metabolite of Brinzolamide, is a carbonic anhydrase (CA) inhibitor with a Kd of 0.136 nM for CA II and an IC50 of 165 nM for CA IV[1].
References
[1] Qinhua Huang, et al. Design, synthesis, and evaluation of NO-donor containing carbonic anhydrase inhibitors to lower intraocular pressure. J Med Chem. 2015 Mar 26;58(6):2821-33. DOI:10.1021/acs.jmedchem.5b00043
O-desmethyl Brinzolamide (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
O-desmethyl Brinzolamide (hydrochloride) Suppliers
Global( 5)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 26070 | 58 |
| Cayman Chemical Company | 800-364-9897 | sales@caymanchem.com | China | 6838 | 58 |
| Aoki Biotechnology (Shenzhen) Co., Ltd. | 18566777408 | CHINA | 0 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
| Cayman Chemical Company | 58 |
| Aoki Biotechnology (Shenzhen) Co., Ltd. | 58 |
O-desmethyl Brinzolamide (hydrochloride)
2967475-56-3