L803-mts
- CAS No.
- 706785-93-5
- Chemical Name:
- L803-mts
- Synonyms
- CBNumber:
- CB715671517
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
L803-mts Chemical Properties,Uses,Production
Uses
L803-mts (Myristoylated L 803) is a selective and substrate-competitive GSK-3 peptide inhibitor (IC50: 40 μM). L803-mts also reduces Aβ deposits and ameliorates cognitive deficits in 5XFAD mice. L803-mts shows antidepressive effect in the forced swimming test[1][2].
References
[1] Kaidanovich-Beilin O, et al. Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus. Biol Psychiatry. 2004 Apr 15;55(8):781-4. DOI:10.1016/j.biopsych.2004.01.008
[2] Avrahami L, et al. Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the Alzheimer disease mouse model: in vivo and in vitro studies. J Biol Chem. 2013 Jan 11;288(2):1295-306. DOI:10.1074/jbc.M112.409250
L803-mts Preparation Products And Raw materials
Raw materials
Preparation Products
L803-mts Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | Eric@peptidego.com | China | 7223 | 58 |
| Supplier | Advantage |
|---|---|
| Hangzhou Peptidego Biotech Co.,Ltd. | 58 |