ANTI-ASPARTYL PROTEASE 2
- CAS No.
- Chemical Name:
- ANTI-ASPARTYL PROTEASE 2
- Synonyms
- ANTI-BACE 1 (EE-17);ANTI-BACE 1 (LK-16);ANTI-BETA-SECRETASE 1;ANTI-ASPARTYL PROTEASE 2;POLYCLONAL ANTIBODY TO BACE1;Anti-β-Site APP Cleaving Enzyme;Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit;Anti-BACE 1, C-Terminus (485-501) antibody produced in rabbit
- CBNumber:
- CB7204454
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD03454775
- MOL File:
- Mol file
ANTI-ASPARTYL PROTEASE 2 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B0806 | Anti-BACE 1, C-Terminus (485-501) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 0.2mL | $558 | 2026-04-30 | Buy | |
| Sigma-Aldrich | B0681 | Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 0.2mL | $558 | 2026-04-30 | Buy |
ANTI-ASPARTYL PROTEASE 2 Chemical Properties, Uses, Production
Uses
Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit has been used in western blotting.
General Description
The membrane-associated aspartic protease BACE-1 (β-site APP cleaving enzyme, Asp2 or memapsin 2) has been identified as β-secretase. BACE-1 constitutes the predominant β-secretase activity in human brain tissue. It is highly expressed in neurons, the major site of Aβ generation. BACE-1 is localized within the Golgi and endosomal compartments, among the several intracellular sites where Aβ is thought to be produced. BACE-1 is initially an inactive proenzyme and localized in endoplasmic reticulum.
Biochem/physiol Actions
Overexpression of β-site APP cleaving enzyme, Asp2 or memapsin 2 (BACE-1) leads to increased β-secretase activity while displaying appropriate cleavage site specificity for APP. The N-glycosylation and phosphorylation of BACE-1 within its C-terminal domain regulated its intracellular trafficking.
ANTI-ASPARTYL PROTEASE 2 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-ASPARTYL PROTEASE 2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| JiangSu Star Science Co.,Ltd | 400-605-7200 15335295587 | 3941881028@qq.com | China | 3755 | 58 |
| Supplier | Advantage |
|---|---|
| JiangSu Star Science Co.,Ltd | 58 |
