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GYKI 47261 DIHYDROCHLORIDE

CAS No.
220445-20-5
Chemical Name:
GYKI 47261 DIHYDROCHLORIDE
Synonyms
GYKI 47261 DIHYDROCHLORIDE;Benzenamine, 4-(8-chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-yl)-;4-(8-Chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-benzeneaminedihydrochloride
CBNumber:
CB72458642
Molecular Formula:
C18H15ClN4
Molecular Weight:
322.79
MDL Number:
MFCD11519959
MOL File:
220445-20-5.mol
Last updated:2023-05-18 11:31:09

GYKI 47261 DIHYDROCHLORIDE Properties

storage temp. Store at +4°C
solubility <35.92mg/ml in DMSO
form solid
color Yellow
FDA UNII 05588G41R2

GYKI 47261 DIHYDROCHLORIDE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 3099 GYKI47261dihydrochloride ≥99%(HPLC) 220445-20-5 10 $214 2021-12-16 Buy
Tocris 3099 GYKI47261dihydrochloride ≥99%(HPLC) 220445-20-5 50 $897 2021-12-16 Buy
TRC G932013 GYKI47261dihydrochloride 220445-20-5 10mg $165 2021-12-16 Buy
Usbiological 255422 GYKI 47261 dihydrochloride 220445-20-5 10mg $480 2021-12-16 Buy
American Custom Chemicals Corporation CHM0152529 GYKI-47261 95.00% 220445-20-5 5MG $499.19 2021-12-16 Buy
Product number Packaging Price Buy
3099 10 $214 Buy
3099 50 $897 Buy
G932013 10mg $165 Buy
255422 10mg $480 Buy
CHM0152529 5MG $499.19 Buy

GYKI 47261 DIHYDROCHLORIDE Chemical Properties,Uses,Production

Uses

GYKI 47261 dihydrochloride is a non-competitive AMPA antagonist receptor.

Biological Activity

Non-competitive AMPA receptor antagonist (IC 50 = 2.5 μ M). Displays broad spectrum anticonvulsive activity and neuroprotective effects in vivo .

References

[1]. abrahám g, sólyom s, csuzdi e, et al. new non competitive ampa antagonists. bioorg med chem, 2000, 8(8): 2127-2143.
[2]. tamási v, hazai e, porsmyr-palmertz m, et al. gyki-47261, a new ampa [2-amino-3-(3-hydroxymethylisoxazole-4-yl)propionic acid] antagonist, is a cyp2e1 inducer. drug metab dispos, 2003, 31(11): 1310-1314.
[3]. bibbiani f, oh jd, kielaite a, et al. combined blockade of ampa and nmda glutamate receptors reduces levodopa-induced motor complications in animal models of pd. exp neurol, 2005, 196(2): 422-429.

GYKI 47261 DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

GYKI 47261 DIHYDROCHLORIDE Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44843 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
JinOu Biomedical (Nanjing) Co., Ltd. 13000000000 jinoupharma@163.com China 11732 58
ApexBio Technology -- sales@apexbt.com United States 6254 58
GYKI 47261 DIHYDROCHLORIDE 4-(8-Chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-benzeneaminedihydrochloride Benzenamine, 4-(8-chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-yl)- 220445-20-5 C18H15ClN42HCl