GYKI 47261 DIHYDROCHLORIDE
- CAS No.
- 220445-20-5
- Chemical Name:
- GYKI 47261 DIHYDROCHLORIDE
- Synonyms
- GYKI 47261 DIHYDROCHLORIDE;Benzenamine, 4-(8-chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-yl)-;4-(8-Chloro-2-methyl-11H-imidazo[1,2-c][2,3]benzodiazepin-6-benzeneaminedihydrochloride
- CBNumber:
- CB72458642
- Molecular Formula:
- C18H15ClN4
- Molecular Weight:
- 322.79
- MDL Number:
- MFCD11519959
- MOL File:
- 220445-20-5.mol
| storage temp. | Store at +4°C |
|---|---|
| solubility | <35.92mg/ml in DMSO |
| form | solid |
| color | Yellow |
| FDA UNII | 05588G41R2 |
GYKI 47261 DIHYDROCHLORIDE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 3099 | GYKI47261dihydrochloride ≥99%(HPLC) | 220445-20-5 | 10 | $214 | 2021-12-16 | Buy |
| Tocris | 3099 | GYKI47261dihydrochloride ≥99%(HPLC) | 220445-20-5 | 50 | $897 | 2021-12-16 | Buy |
| TRC | G932013 | GYKI47261dihydrochloride | 220445-20-5 | 10mg | $165 | 2021-12-16 | Buy |
| Usbiological | 255422 | GYKI 47261 dihydrochloride | 220445-20-5 | 10mg | $480 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0152529 | GYKI-47261 95.00% | 220445-20-5 | 5MG | $499.19 | 2021-12-16 | Buy |
GYKI 47261 DIHYDROCHLORIDE Chemical Properties,Uses,Production
Uses
GYKI 47261 dihydrochloride is a non-competitive AMPA antagonist receptor.
Biological Activity
Non-competitive AMPA receptor antagonist (IC 50 = 2.5 μ M). Displays broad spectrum anticonvulsive activity and neuroprotective effects in vivo .
References
[1]. abrahám g, sólyom s, csuzdi e, et al. new non competitive ampa antagonists. bioorg med chem, 2000, 8(8): 2127-2143.
[2]. tamási v, hazai e, porsmyr-palmertz m, et al. gyki-47261, a new ampa [2-amino-3-(3-hydroxymethylisoxazole-4-yl)propionic acid] antagonist, is a cyp2e1 inducer. drug metab dispos, 2003, 31(11): 1310-1314.
[3]. bibbiani f, oh jd, kielaite a, et al. combined blockade of ampa and nmda glutamate receptors reduces levodopa-induced motor complications in animal models of pd. exp neurol, 2005, 196(2): 422-429.
GYKI 47261 DIHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
GYKI 47261 DIHYDROCHLORIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| JinOu Biomedical (Nanjing) Co., Ltd. | 13000000000 | jinoupharma@163.com | China | 11732 | 58 |
| ApexBio Technology | -- | sales@apexbt.com | United States | 6254 | 58 |