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ChemicalBook >> CAS DataBase List >>(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Structure
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one structure
CAS No.
123367-26-0
Chemical Name:
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
Synonyms
Imatinib impurity J;Irutinib Impurity A;(E)-3-(dimethylamino);Imatinib EP impuritiesA;Imatinib Mesilate EP Impurity A;Nilotinib Impurity 16 (Imatinib EP Impurity A);Imatinib EP Impurity A (Nilotinib Impurity 16);(E)-3-(Dimethylamino)-1-(3-pyridyl)-2-propen-1-one;(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one;(2E)-3-(Dimethylamino)-1-(3-Pyridyl)prtop-2-en-1-one
CBNumber:
CB72516261
Molecular Formula:
C10H12N2O
Molecular Weight:
176.22
MDL Number:
MFCD00115180
MOL File:
123367-26-0.mol
MSDS File:
SDS
Last updated:2024-04-02 15:44:47
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(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Properties

Melting point 113℃
Boiling point 281℃
Density 1.070
Flash point 124℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 4.74±0.70(Predicted)
color Dark Brown to Very Dark Brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D462115 (2E)​-​3-​(Dimethylamino)​-​1-​(3-​pyridyl)​prop-​2-​en-​1-​one 123367-26-0 250mg $50 2021-12-16 Buy
SynQuest Laboratories 4H56-1-DW (2E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one 98.0% 123367-26-0 250mg $65 2021-12-16 Buy
SynQuest Laboratories 4H56-1-DW (2E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one 98.0% 123367-26-0 1g $95 2021-12-16 Buy
SynQuest Laboratories 4H56-1-DW (2E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one 98.0% 123367-26-0 5G $295 2021-12-16 Buy
Alichem 123367260 (E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one 123367-26-0 500g $296.8 2021-12-16 Buy
Product number Packaging Price Buy
D462115 250mg $50 Buy
4H56-1-DW 250mg $65 Buy
4H56-1-DW 1g $95 Buy
4H56-1-DW 5G $295 Buy
123367260 500g $296.8 Buy

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Chemical Properties,Uses,Production

Description

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one is a pharmaceutical intermediate used as an intermediate of nilotinib, a targeted anticancer drug for the treatment of chronic myeloid leukaemia (CML).

Uses

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one acts as a reagent for the synthesis of oxindole-linked indolyl-pyrimidine derivatives which are potential cytotoxic agents.

Solubility in organics

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one is soluble in chloroform and dichloromethane.

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one Suppliers

Global( 96)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Lianyungang happen teng technology co., LTD 		15950718863 wang666xt@163.com CHINA 295 58
HaBo Hong Kong Co., Limited. 		+86-25-18512596065 info@habotech.com CHINA 933 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49390 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23556 58
Finetech Industry Limited 		+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9702 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Lianyungang happen teng technology co., LTD 		58
HaBo Hong Kong Co., Limited. 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
ANHUI WITOP BIOTECH CO., LTD 		58
Finetech Industry Limited 		58

View Lastest Price from (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one pictures 2022-06-23 (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
123367-26-0
 US $1.00 / g 10g 98% 10tons Yangzhou Qinyuan Pharmatech Co.,ltd
(2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one pictures 2019-12-26 (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one
123367-26-0
 US $1.00 / g 1g ≥98% g/kg/Ton Career Henan Chemical Co

123367-26-0((2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one)Related Search:

N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine 2-Propen-1-one, 1-[(3R)-3-[4-amino-7-oxido-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]- Imatinib Impurity 38 Ibrutinib Impurity 28 (R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone
Imatinib Impurity 4 Ibrutinib Impurity 5 Ibrutinib Dimer Impurity Imatinib Impurity 7 (S)-Ibrutinib
(R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one 1-Piperidinecarboxylic acid, 3-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-, 1,1-diMethylethyl ester, (3R)- N-(2-Methyl-4-nitrophenyl)-4-(3-pyridinyl)-2-pyrimidinamine N-DESMETHYL IMATINIB 4-Chloromethyl-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide
Ilutinib Methylxanthate Impurity C Ibrutinib Impurity D N-(3-GUANIDINO-4-METHYLPHENYL)-4-(METHYLPIPERAZINE-1-YL-METHYL)BENZAMIDE

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(2E)-3-(DiMethylaMino)-1-(pyridin-3-yl)prop-2-en-1-one (2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one (IMpurity of Nilotinib) (2E)-3-(Dimethylamino)-1-(3-pyridyl)prop-2-en-1-one (E)-3-(Dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one Nilotinib IMpurity ((2E)-3-(DiMethylaMino)-1-(3-pyridyl)prop-2-en-1-one) Imatinib EP Impurity A (Nilotinib Impurity 16) Nilotinib Impurity 16 (Imatinib EP Impurity A) Imatinib impurity 14/(E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one (E)-3-(dimethylamino) Irutinib Impurity A Imatinib impurity J 2-Propen-1-one, 3-(dimethylamino)-1-(3-pyridinyl)-, (2E)- (E)-3-(Dimethylamino)-1-(3-pyridyl)-2-propen-1-one Imatinib EP impuritiesA Imatinib Mesilate EP Impurity A (2E)-3-(Dimethylamino)-1-(3-Pyridyl)prtop-2-en-1-one 123367-26-0