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Raseglurant

CAS No.
757950-09-7
Chemical Name:
Raseglurant
Synonyms
Raseglurant;Raseglurant/ADX-10059;2-((3-Fluorophenyl)ethynyl)-4,6-dimethylpyridin-3-amine;2-[2-(3-fluorophenyl)ethynyl]-4,6-dimethyl-3-Pyridinamine;2-(3-Fluoro-phenylethynyl)-4,6-dimethyl-pyridin-3-ylamine;3-Pyridinamine, 2-[2-(3-fluorophenyl)ethynyl]-4,6-dimethyl-
CBNumber:
CB72628348
Molecular Formula:
C15H13FN2
Molecular Weight:
240.28
MDL Number:
MFCD18785292
MOL File:
757950-09-7.mol
Last updated:2025-04-18 09:52:42
Product description Number Pack Size Price
RASEGLURANT 95.00% INB0005571 5MG $504.77
RASEGLURANT 95.00% INB0005571 1G $1012.2

Raseglurant Properties

Boiling point 431.2±45.0 °C(Predicted)
Density 1.20±0.1 g/cm3(Predicted)
pka 4.18±0.37(Predicted)
FDA UNII 66UCJ8Z8L1

Raseglurant price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation INB0005571 RASEGLURANT 95.00% 757950-09-7 5MG $504.77 2021-12-16 Buy
American Custom Chemicals Corporation INB0005571 RASEGLURANT 95.00% 757950-09-7 1G $1012.2 2021-12-16 Buy
Product number Packaging Price Buy
INB0005571 5MG $504.77 Buy
INB0005571 1G $1012.2 Buy

Raseglurant Chemical Properties,Uses,Production

Uses

Raseglurant (ADX-10059) is a mGlu5 receptor negative allosteric modulator. Raseglurant is effective against migraine. Raseglurant reduces the Haloperidol (HY-14538)-induced catalepsy in mice[1][2].

References

[1] Romero-Fernandez W, et al. The mGlu5 Receptor Protomer-Mediated Dopamine D2 Receptor Trans-Inhibition Is Dependent on the Adenosine A2A Receptor Protomer: Implications for Parkinson's Disease. Mol Neurobiol. 2022 Oct;59(10):5955-5969. DOI:10.1007/s12035-022-02946-9
[2] Font J, et al. Correction: Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator. Elife. 2018 Jan 8;7:e34752. DOI:10.7554/eLife.34752

Raseglurant Preparation Products And Raw materials

Raw materials

Preparation Products

Raseglurant Suppliers

Global( 10)Suppliers
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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Shanghai Shengxiu Biotechnology Co., Ltd. 13761144602 3896578657@qq.com China 4484 58
Shanghai Xinketai Biotechnology Co., Ltd 18043446684 3622784229@qq.com China 523 58
Raseglurant 2-(3-Fluoro-phenylethynyl)-4,6-dimethyl-pyridin-3-ylamine 2-[2-(3-fluorophenyl)ethynyl]-4,6-dimethyl-3-Pyridinamine 3-Pyridinamine, 2-[2-(3-fluorophenyl)ethynyl]-4,6-dimethyl- Raseglurant/ADX-10059 2-((3-Fluorophenyl)ethynyl)-4,6-dimethylpyridin-3-amine 757950-09-7