1-Pyrrolidinecarboxylic acid, 2-(hydroxydiphenylmethyl)-,1,1-dimethylethyl ester, (2R)-

CAS No.
137496-68-5
Chemical Name:
1-Pyrrolidinecarboxylic acid, 2-(hydroxydiphenylmethyl)-,1,1-dimethylethyl ester, (2R)-
Synonyms
(R)-tert-Butyl 2-(hydroxydiphenylmethyl)pyrrolidine-1-carboxylate;1-Pyrrolidinecarboxylic acid, 2-(hydroxydiphenylmethyl)-,1,1-dimethylethyl ester, (2R)-
CBNumber:
CB73076496
Molecular Formula:
C22H27NO3
Molecular Weight:
353.45
MDL Number:
MOL File:
137496-68-5.mol
Last updated:2023-07-14 17:27:17

1-Pyrrolidinecarboxylic acid, 2-(hydroxydiphenylmethyl)-,1,1-dimethylethyl ester, (2R)- Properties

Melting point 151-152 °C(Solv: ethyl acetate (141-78-6))
Boiling point 490.7±25.0 °C(Predicted)
Density 1.152±0.06 g/cm3(Predicted)
solubility soluble in Ethyl Acetate; Chloroform;
form Solid
pka 13.15±0.29(Predicted)
color White

1-Pyrrolidinecarboxylic acid, 2-(hydroxydiphenylmethyl)-,1,1-dimethylethyl ester, (2R)- Chemical Properties,Uses,Production

Uses

(R)-tert-Butyl 2-(hydroxydiphenylmethyl)pyrrolidine-1-carboxylate is an intermediate for the synthesis of (4R)-4-(1-Methylethyl)-2-cyclohexen-1-one (M223865), which is used in the preparation of kalihinol analogs having antimalarial properties.

1-Pyrrolidinecarboxylic acid, 2-(hydroxydiphenylmethyl)-,1,1-dimethylethyl ester, (2R)- Preparation Products And Raw materials

Raw materials

Preparation Products

1-Pyrrolidinecarboxylic acid, 2-(hydroxydiphenylmethyl)-,1,1-dimethylethyl ester, (2R)- Suppliers

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(R)-tert-Butyl 2-(hydroxydiphenylmethyl)pyrrolidine-1-carboxylate 1-Pyrrolidinecarboxylic acid, 2-(hydroxydiphenylmethyl)-,1,1-dimethylethyl ester, (2R)- 137496-68-5