Anti-Calbindin-D-28K antibody, Mouse monoclonal
- CAS No.
- Chemical Name:
- Anti-Calbindin-D-28K antibody, Mouse monoclonal
- Synonyms
- Anti-Calbindin-D-28K antibody, Mouse monoclonal
- CBNumber:
- CB74669084
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-Calbindin-D-28K antibody, Mouse monoclonal price More Price(1)
Anti-Calbindin-D-28K antibody, Mouse monoclonal Chemical Properties,Uses,Production
Uses
- Anti-Calbindin-D-28K antibody, Mouse monoclonal has been used in:
- western blotting
- enzyme-linked immunosorbent assay (ELISA){31
- immunohistochemistry
- immunohistochemical procedure
- indirect immunofluorescence
General Description
Calbindin-D-28K (CALB1) is encoded by the gene mapped to human chromosome 8q21.3-q22.1. CALB1 belongs to the EF hand superfamily of Ca2+ binding proteins (CBPs). The encoded protein contains EF hand motif involved in the specific and reversible binding of Ca2+. It is highly expressed in specific regions of central nervous system such as cerebellar Purkinje cells and hippocampal granule cells.
Biochem/physiol Actions
Calbindin D-28k might play a vital role as an intracellular Ca2+ buffer. It has an ability to protect nerve cells from calcium-mediated neurotoxicity. The encoded protein functions as a potent neuroanatomical marker which can be used to selectively visualize certain neurons and pathways in the central nervous system and peripheral nervous system. Mutations in the gene has been observed in patients with Parkinson′s disease (PD).
Anti-Calbindin-D-28K antibody, Mouse monoclonal Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-Calbindin-D-28K antibody, Mouse monoclonal Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
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Sigma-Aldrich | 80 |