ANTI-HUMAN CD166
- CAS No.
- Chemical Name:
- ANTI-HUMAN CD166
- Synonyms
- ANTI-ALCAM;ANTI-CD166;ANTI-HUMAN CD166;ANTI-ALCAM (HUMAN);ANTI-CD166 (HUMAN);Anti-ALCAM antibody produced in rabbit;ANTI-ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE;Anti-CD166 antigen precursor antibody produced in rabbit;Anti-Activated leukocyte-cell adhesion molecule antibody produced in rabbit
- CBNumber:
- CB7473481
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01865427
- MOL File:
- Mol file
ANTI-HUMAN CD166 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | HPA010926 | Anti-ALCAM antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $294 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA010926 | Anti-ALCAM antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $547 | 2024-03-01 | Buy | |
| American Custom Chemicals Corporation | ATB0016360 | ANTI-ALCAM 95.00% | 5MG | $499.02 | 2021-12-16 | Buy |
ANTI-HUMAN CD166 Chemical Properties,Uses,Production
Uses
Anti-ALCAM antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
General Description
Activated leukocyte cell adhesion molecule (ALCAM) belongs to the superfamily of immunoglobulin cell adhesion molecules (Ig-CAMs). Its extracellular domain consist of five immunoglobulin (Ig)-like domains, which aid in cell-cell adhesion, either through heterophilic (ALCAM-CD6) or homophilic (ALCAM-ALCAM) interactions. It is a type I transmembrane protein. It has a short cytoplasmic tail and a transmembrane region, and has a molecular weight of 110kDa. It is expressed in a wide range of tissues, especially in the epithelia and the corresponding cancers. ALCAM gene maps to human chromosome 3q13.1-q13.2.
Biochem/physiol Actions
Activated leukocyte cell adhesion molecule (ALCAM) mediates cell-cell adhesion, either through heterophilic (ALCAM-CD6) or homophilic (ALCAM-ALCAM) interactions. Hemophilic interactions aid in cell migration and invasiveness of tumor cells. ALCAM present on dendritic cells, induces T-cell activation by interacting with cluster of differentiation 6 (CD6) present on T-cells. This heterophilic interaction is necessary for the stabilization of immunological synapses. It mediates the extravasation of leukocytes and their transport to the central nervous system, as well as axonal fasciculation. Colorectal cancer patients, who show increased levels of ALCAM shedding, have poor prognosis and survival rates. The soluble form of ALCAM is related to the aggressive type II phenotype of epithelial ovarian cancer, and can be used as a marker for the same.
ANTI-HUMAN CD166 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-HUMAN CD166 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Bohu Biotechnology Co., LTD | 021-57763112 13585886131 | 3004987436@qq.com | China | 9694 | 58 |
| Supplier | Advantage |
|---|---|
| Shanghai Bohu Biotechnology Co., LTD | 58 |