ChemicalBook >> CAS DataBase List >>(2S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid TFA
(2S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid TFA
- CAS No.
- 1269794-89-9
- Chemical Name:
- (2S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid TFA
- Synonyms
- GCPII-IN-1 TFA;(2S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid TFA;(S)-5-carboxy-5-(3-((S)-13-dicarboxypropyl)ureido)pentan-1-amine trifluoroacetate salt;(S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid compound with 2,2,2-trifluoroacetic acid (1:1)
- CBNumber:
- CB75465942
- Molecular Formula:
- C14H22F3N3O9
- Molecular Weight:
- 433.34
- MDL Number:
- MFCD32901379
- MOL File:
- 1269794-89-9.mol
Last updated:2023-05-21 10:59:17
(2S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid TFA Chemical Properties,Uses,Production
Biological Activity
GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII, or PSMA) inhibitor scaffold with a Ki of 44.3 nM[1].
References
[1]. Jan Tykvart, et al. Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. Bioorg Med Chem. 2014 Aug 1;22(15):4099-108.
Synthesis of (2S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid TFA from (S)-Di-Tert-Butyl 2-(3-((S)-6-Amino-1-(Tert-Butoxy)-1-Oxohexan-2-Yl)Ureido)Pentanedioate and Trifluoroacetic acid
(2S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid TFA Preparation Products And Raw materials
Raw materials
Preparation Products
(2S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid TFA Suppliers
Global( 8)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9425 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Nanjing Peiwill Biotechnology Co.,Ltd. | 025-57027729 15850702895 | 15850702895@163.com | China | 72 | 55 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | eric@peptidego.com | China | 6347 | 58 |
| Nanchang Tianzhen Biotechnology Co., Ltd | 13173652190 | pomy@tanzhenbio.com | China | 1594 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24018 | 58 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 5950 | 58 |
| Henan Alpha Chemical Co., Ltd. | 0371-55013243 15324716602 | 2853979810@qq.com | China | 9957 | 58 |
(2S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid TFA
(S)-2-(3-((S)-5-amino-1-carboxypentyl)ureido)pentanedioic acid compound with 2,2,2-trifluoroacetic acid (1:1)
GCPII-IN-1 TFA
(S)-5-carboxy-5-(3-((S)-13-dicarboxypropyl)ureido)pentan-1-amine trifluoroacetate salt
1269794-89-9