Mirvetuximab Soravtansine
- CAS No.
- 1453084-37-1
- Chemical Name:
- Mirvetuximab Soravtansine
- Synonyms
- Mirvetuximab Soravtansine;Mirvetuximab soravtansine (ADC)
- CBNumber:
- CB78080957
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | 98DE7VN88D |
| NCI Drug Dictionary | mirvetuximab soravtansine |
Mirvetuximab Soravtansine Chemical Properties,Uses,Production
Uses
Mirvetuximab soravtansine (IMGN853) solution is an anti-folate receptor α (FRα) antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A. Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage[1].
in vivo
Mirvetuximab soravtansine (IMGN853; 5 mg/kg; i.v.; female severe combined immunodeficient (SCID) mice with patient-derived xenografts) potentiates the antitumor activity of Carboplatin in vivo[1].
References
[1] Ponte JF, et, al. Mirvetuximab Soravtansine (IMGN853), a Folate Receptor Alpha-Targeting Antibody-Drug Conjugate, Potentiates the Activity of Standard of Care Therapeutics in Ovarian Cancer Models. Neoplasia. 2016 Dec;18(12):775-784. DOI:10.1016/j.neo.2016.11.002
Mirvetuximab Soravtansine Preparation Products And Raw materials
Raw materials
Preparation Products
Mirvetuximab Soravtansine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39035 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10308 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| Wuhan Peptide Core Biotechnology Co., Ltd | 027-65317797 13667154760 | 1096814016@qq.com | China | 10711 | 58 |
| bioleaper | 4000880777 17585207275 | guojing@bioleaper.com | China | 5616 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29257 | 58 |
| Atagenix Laboratories | 027-87008169 17762441161 | info@atagenix.com | China | 10001 | 58 |
| Aikon International Limited | 025-58851090 13408877820 | 2850281427@qq.com | China | 10000 | 58 |
View Lastest Price from Mirvetuximab Soravtansine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-04 | Mirvetuximab soravtansine
1453084-37-1
|
US $2540.00-923.00 / mg | 95.00% | 10g | TargetMol Chemicals Inc. |
-
- Mirvetuximab soravtansine
1453084-37-1
- US $2540.00-923.00 / mg
- 95.00%
- TargetMol Chemicals Inc.
