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S39625
- CAS No.
- 536711-20-3
- Chemical Name:
- S39625
- Synonyms
- S39625;S-39625;S 39625
- CBNumber:
- CB811075558
- Molecular Formula:
- C25H22N2O5
- Molecular Weight:
- 430.46
- MDL Number:
- MOL File:
- 536711-20-3.mol
Last updated:2023-03-31 09:12:57
S39625 Chemical Properties,Uses,Production
Description
S39625 is an E-ring camptothecin keto analogue. S39625 is stable, potent, and selective topoisomerase I inhibitor without being substrates of drug efflux transporters. Nanomolar concentrations of S39625 induces intense and persistent histone gamma-H2AX. The chemical stability of the keto analogues and the ability of S39625 to produce high levels of persistent Top1-DNA cleavage complex and its potent antiproliferative activity against human cancer cell lines make S39625 a promising new anticancer drug candidate. Histone gamma-H2AX could be used as a biomarker for the upcoming clinical trials of S39625.
S39625 Preparation Products And Raw materials
Raw materials
Preparation Products
S39625 Suppliers
Global( 2)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
S 39625
S39625
S-39625
536711-20-3