ChemicalBook >> CAS DataBase List >>CG-0009
CG-0009
- CAS No.
- 944744-57-4
- Chemical Name:
- CG-0009
- Synonyms
- CG0009;CG-0009;CG 0009
- CBNumber:
- CB811075679
- Molecular Formula:
- C26H31N7O
- Molecular Weight:
- 457.58
- MDL Number:
- MOL File:
- 944744-57-4.mol
Last updated:2023-03-31 09:12:58
CG-0009 Chemical Properties,Uses,Production
Description
CG0009 is a potent and selective a Glycogen Synthase Kinase 3 (GSK3) inhibitor. CG0009, inhibits proliferation, induces apoptosis cell death, and activates the p53-Bax pathway in breast cancer cells, predominantly via cyclin D1 depletion. CG0009 induces significant growth inhibition and cell death in breast cancer cell lines, with a wide range of IC50 values (between 0.49 (MCF7) and 11 μM (NCI/ADR-RES and BT549)). CG0009 inhibits breast cancer cell growth through cyclin D1 depletion and p53 activation, and may thus offer an innovative therapeutic approach for breast cancers resistant to hormone-based therapy.
CG-0009 Preparation Products And Raw materials
Raw materials
Preparation Products
CG-0009 Suppliers
Global( 2)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
CG 0009
CG0009
CG-0009
944744-57-4