Anti-PFN1

CAS No.
Chemical Name:
Anti-PFN1
Synonyms
Anti-PFN1;Monoclonal Anti-Profilin 1 antibody produced in mouse;Anti-Profilin 1 (C-terminal) antibody produced in rabbit;Anti-Profilin 1 (N-terminal) antibody produced in rabbit
CBNumber:
CB82093600
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD09265368
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

Anti-PFN1 Properties

storage temp. -20°C
form buffered aqueous solution

Anti-PFN1 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P7749 Anti-Profilin 1 (N-terminal) antibody produced in rabbit ~1?mg/mL, affinity isolated antibody, buffered aqueous solution 200μL $648 2024-03-01 Buy
Sigma-Aldrich P7624 Anti-Profilin 1 (C-terminal) antibody produced in rabbit ~1?mg/mL, affinity isolated antibody, buffered aqueous solution 200μL $209.6 2024-03-01 Buy
Product number Packaging Price Buy
P7749 200μL $648 Buy
P7624 200μL $209.6 Buy

Anti-PFN1 Chemical Properties,Uses,Production

Uses

Anti-Profilin 1 (N-terminal) antibody produced in rabbit has been used in immunoblotting and immunofluorescence.

General Description

Anti-Profilin 1 (N-terminal) is developed in rabbit using as immunogen a synthetic peptide corresponding to amino acid residues of human profilin 1, conjugated to keyhole limpet hemocyanin (KLH). Profilin 1 is a ubiquitous actin monomer-binding protein. Profilin 1 is highly expressed throughout development and adulthood in most of the tissues including brain.

Biochem/physiol Actions

Profilin 1 is involved in actin polymerization in response to extracellular signals. Profilins were shown to be important for normal cell proliferation, differentiation and motility. Deletion of profilin 1 gene leads to an embryonic lethal phenotype. Profilin 1 is a potent regulator of actin filament dynamics. Although profilin 1 prevents spontaneous actin polymerization by complexing with unpolymerized actin in vivo, actin-profilin complexes can be added to free barbed ends, thereby stimulating actin polymerization. Profilin 1 was suggested to act as a tumor suppressor protein based on its reduced expression in several types of invasive cancers and its ability to suppress tumorigenicity when over-expressed in breast cancer cells. Deletion of profilin 1 is associated with Miller-Dieker syndrome.

Anti-PFN1 Preparation Products And Raw materials

Raw materials

Preparation Products

Anti-PFN1 Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
Anti-Profilin 1 (N-terminal) antibody produced in rabbit Anti-PFN1 Anti-Profilin 1 (C-terminal) antibody produced in rabbit Monoclonal Anti-Profilin 1 antibody produced in mouse