Anti-α-Catenin
- CAS No.
- Chemical Name:
- Anti-α-Catenin
- Synonyms
- Anti-CTNB1;Anti-CATNB;Anti-CTNNB;Anti-CTNNB1;Anti-FLJ37923;Anti-FLJ25606;Anti-α-Catenin;Anti-DKFZp686D02253;Anti-CTNNB1 antibody produced in rabbit;Anti-CTNNB1 (AB1) antibody produced in rabbit
- CBNumber:
- CB82096580
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00282178
- MOL File:
- Mol file
Anti-α-Catenin price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | WH0001499M2 | Monoclonal Anti-CTNNB1 antibody produced in mouse clone 1C9, purified immunoglobulin, buffered aqueous solution | 100μg | $524 | 2024-03-01 | Buy | |
Sigma-Aldrich | SAB4300630 | Anti-phospho-β-catenin (pTyr333) antibody produced in rabbit affinity isolated antibody | 100μg | $511 | 2024-03-01 | Buy | |
Sigma-Aldrich | HPA029160 | Anti-CTNNB1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, ab2 | 100μL | $514 | 2024-03-01 | Buy | |
Sigma-Aldrich | HPA029159 | Anti-CTNNB1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $514 | 2024-03-01 | Buy | |
Sigma-Aldrich | C2081 | Anti-α-Catenin antibody produced in rabbit whole antiserum | 0.2mL | $402 | 2024-03-01 | Buy |
Anti-α-Catenin Chemical Properties,Uses,Production
Uses
Anti-α-Catenin antibody has been used:
- in dot blot immunoassay
- in immunoblotting
- in immunofluorescence
- in western blotting
- in immunoprecipitation
- in immunofluorescence staining
- in coimmunoprecipitation
General Description
Catenin are distinct peripheral cytosolic proteins, α, β, and γ -catenin (102 kDa, 94 kDa and 86 kDa, respectively) are found in varying abundance in many developing and adult tissues. Within its conserved regions, α-catenin shows 30% identity to vinculin, a protein found mainly in focal cell-cell and cell substrate adhesions.
Biochem/physiol Actions
Catenins bind, directly or indirectly, to the conserved cytoplasmic tail domain of the cell-adhesion cadherins. Cadherins are transmembrane cell surface glycoprotein molecules that mediate calcium-dependent intercellular interactions and are important for tissue morphogenesis. Catenins link E-cadherin to other integral membrane proteins such as Na+ /K+ -ATPase, or to cytoplasmic proteins such as fodrin, ankyrin, sarcoma (Src) and Yes kinases and are modulated by Wnt-1 protooncogene. They are considered good candidates for mediating transduction of cell-cell contact positional signals to the cell interior. α-Catenin appears to be capable of interacting with N-cadherin and P-cadherin. Absence of α-catenin is found in certain tumor cell lines. Frequent reduction of α-catenin levels in human carcinomas of the esophagus, stomach and colon is also reported. Prostate cancer development appears to be correlated with α-catenin gene deletions.
Anti-α-Catenin Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-α-Catenin Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Shanghai Bohu Biotechnology Co., LTD | 021-57763112 13585886131 | 3004987436@qq.com | China | 9694 | 58 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |
Shanghai Bohu Biotechnology Co., LTD | 58 |