DifloMotecan
- CAS No.
- 220997-97-7
- Chemical Name:
- DifloMotecan
- Synonyms
- BN 80915;Difloomotecan;PubChem ID: 219023;3H,15H-Oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione, 5-ethyl-9,10-difluoro-1,4,5,13-tetrahydro-5-hydroxy-, (5R)-
- CBNumber:
- CB82582832
- Molecular Formula:
- C21H16F2N2O4
- Molecular Weight:
- 398.36
- MDL Number:
- MFCD09837794
- MOL File:
- 220997-97-7.mol
| FDA UNII | QKT1LC4J1P |
|---|
DifloMotecan Chemical Properties,Uses,Production
Uses
Difloomotecan is a homocamptothecin that targets DNA topoisomerase I. Difloomotecan is used in cancer therapy.
Definition
ChEBI: Diflomotecan is an organic heteropentacyclic compound that is (5R)-8-[(6,7-difluoroquinolin-3-yl)methyl]-5-ethyl-5-hydroxy-1,4,5,8-tetrahydrooxepino[3,4-c]pyridine-3,9-dione in which position 7 of the oxepinopyridine moiety is joined to position 3 of the difluoroquinoine ring by a single bond. An E-ring modified camptothecin analogue that has greater lactone stability in plasma compared with other topoisomerase I inhibitors. It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an antineoplastic agent. It is an organic heteropentacyclic compound, an organofluorine compound, a tertiary alcohol, an epsilon-lactone and an organonitrogen heterocyclic compound. It is functionally related to a (R)-homocamptothecin.
DifloMotecan Preparation Products And Raw materials
Raw materials
Preparation Products
DifloMotecan Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shochem(Shanghai) Co.,Ltd | 86-21-50800795 | info@shochem.com | CHINA | 288 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2210 | 55 |
| Lanzhou Angeli Biochemical Technology Co., Ltd. | 0931-8235634 13321316780 | 1455540579@qq.com | China | 959 | 55 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44843 | 58 |
| Shanghai Easy CDMO Co.,Ltd | 021-61734564 | August@easycdmo.com | China | 10010 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | ET-market@chemextension.com | China | 24495 | 58 |