9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole

CAS No.
1097883-05-0
Chemical Name:
9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole
Synonyms
CP-352664;9-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,2,3,4,4a,9a-hexahydrocarbazole;9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole
CBNumber:
CB82667032
Molecular Formula:
C18H18N4
Molecular Weight:
290.36232
MDL Number:
MOL File:
1097883-05-0.mol
Last updated:2025-04-18 09:52:52

9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole Chemical Properties,Uses,Production

Uses

CP-352664 is a JAK inhibitor. CP-352664 has a inhibitoinhibits JAK3 with an EC50 value of 210 nM. CP-352664 is promising for research of organ transplant rejection and autoimmune disorders such as rheumatoid arthritis[1].

References

[1] Flanagan ME, et al. Discovery of CP-690,550: a potent and selective Janus kinase (JAK) inhibitor for the treatment of autoimmune diseases and organ transplant rejection. J Med Chem. 2010 Dec 23;53(24):8468-84. DOI:10.1021/jm1004286

9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole Preparation Products And Raw materials

Raw materials

Preparation Products

9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole Suppliers

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TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 23257 58
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9-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole 9-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1,2,3,4,4a,9a-hexahydrocarbazole CP-352664 1097883-05-0