tert-Butyl 3-(2-hydroxyethoxy)propanoate
- CAS No.
- 671802-00-9
- Chemical Name:
- tert-Butyl 3-(2-hydroxyethoxy)propanoate
- Synonyms
- HO-PEG1-CH2CH2COOTBU;OH-PEG1-CH2CH2COOtBu;HO-PEG1-t-Butyl ester;Hydroxy-PEG1-(CH2)2-Boc;Hydroxy-PEG1-t-butyl ester;tert-Butyl 3-(2-hydroxyethoxy)propanoate;2-Methyl-2-propanyl 3-(2-hydroxyethoxy)propanoate;3-(2-hydroxyethoxy)propionic acid tert-butyl ester;3-(2-Hydroxyethoxy)propanoic acid tert-butyl ester;3-(2-Hydroxyethoxy)propanoic acid 1,1-dimethylethyl ester
- CBNumber:
- CB82680372
- Molecular Formula:
- C9H18O4
- Molecular Weight:
- 190.24
- MDL Number:
- MFCD22056310
- MOL File:
- 671802-00-9.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2942000090 |
tert-Butyl 3-(2-hydroxyethoxy)propanoate price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B809905 | tert-Butyl3-(2-hydroxyethoxy)propanoate | 671802-00-9 | 100mg | $50 | 2021-12-16 | Buy |
| BroadPharm | BP-20597 | Hydroxy-PEG1-t-butylester 98% | 671802-00-9 | 10g | $360 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0396313 | TERTBUTYL-3-(2-HYDROXYETHOXY)PROPANOATE 95.00% | 671802-00-9 | 5MG | $495.45 | 2021-12-16 | Buy |
| Crysdot | CD13006963 | tert-Butyl3-(2-hydroxyethoxy)propanoate 95+% | 671802-00-9 | 10g | $579 | 2021-12-16 | Buy |
| Ambeed | A143357 | tert-Butyl3-(2-hydroxyethoxy)propanoate 98% | 671802-00-9 | 25g | $826 | 2021-12-16 | Buy |
tert-Butyl 3-(2-hydroxyethoxy)propanoate Chemical Properties,Uses,Production
Description
Hydroxy-PEG1-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
tert-Butyl 3-(2-hydroxyethoxy)propanoate can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and pharmaceutical and chemical production process.
Uses
tert-Butyl 3-(2-hydroxyethoxy)propanoate is a reactant in the synthesis of hydrophilic aminooxy linked and multivalent disaccharide cellobiose derivatives for chemoselective aldehyde/ketone conjugation
Synthesis
To a solution of anhydrous ethylene glycol (10 g, 161.1 mmol) in anhydrous THF (40 mL) was added sodium metal (62.0 mg, 2.70 mmol) and stirred at room temperature for 2 hours.Add tert-butyl acrylate (6.90, 53.7 mmol) and stir overnight.After quenching with water, the solvent was THF dried under reduced pressure, and extracted with ethyl acetate and water.The organic layer was separated, washed with brine, and dried over Na 2 SO 4.After filtration and evaporation, the residue was purified by silica gel column chromatography (petroleum ether/ethyl acetate = 2:1) to obtain a colorless oil 44 (5.0 g, 26.3 mmol, 49% yield)
tert-Butyl 3-(2-hydroxyethoxy)propanoate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Chengdu Pukang Biotechnology Co., Ltd | 028-82550498 | export@pu-kang.com | CHINA | 210 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| Nanjing Hengbei Chemicals Co., Ltd. | +86-25-58393656 | sales@hengbeichem.cn | China | 6856 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
View Lastest Price from tert-Butyl 3-(2-hydroxyethoxy)propanoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-25 | Hydroxy-PEG1-t-butyl ester
671802-00-9
|
US $0.00 / g | 25g | >98.00% | 25g | Xian confluore Biological Technology Co., Ltd. |
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- Hydroxy-PEG1-t-butyl ester
671802-00-9
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.