Anti-GRB2-associated binding protein 1
- CAS No.
- Chemical Name:
- Anti-GRB2-associated binding protein 1
- Synonyms
- Anti-GAB1 antibody produced in rabbit;Anti-GRB2-associated binding protein 1;Anti-GAB1 (222-235) antibody produced in rabbit
- CBNumber:
- CB82880178
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-GRB2-associated binding protein 1 price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4501061 | Anti-GAB1 antibody produced in rabbit affinity isolated antibody | 100μG | $506 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4501060 | Anti-GAB1 antibody produced in rabbit affinity isolated antibody | 100μG | $506 | 2024-03-01 | Buy |
Anti-GRB2-associated binding protein 1 Chemical Properties,Uses,Production
Uses
Anti-GAB1 antibody produced in rabbit has been used in proximity ligation assay (1:100) and western blotting.
General Description
Anti-GAB1 Antibody detects endogenous levels of total GAB1 protein.
Biochem/physiol Actions
GRB2 associated binding protein 1 (GAB1) acts as a scaffold protein for protein-protein interaction. It regulates growth factor receptors and enhances signal transduction of multiple intracellular signaling pathways, such as phosphatidylinositol 3-kinase and protein kinase B (PKB/AKT)/ mammalian target of rapamycin (mTOR) signaling pathways. Upregulated expression of GAB1 contributes to the progression of various types of cancer including human oral squamous cell carcinoma (OSCC), breast cancer, colorectal cancer, hepatocellular carcinoma, and ovarian cancer. Therefore, knockdown of the GAB1 gene can be considered as a potential therapeutic strategy for treating breast cancer and OSCC.
Anti-GRB2-associated binding protein 1 Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-GRB2-associated binding protein 1 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 6394 | 58 |
| Supplier | Advantage |
|---|---|
| Merck KGaA | 58 |