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Growth hormone releasing peptide

CAS No.
87616-84-0
Chemical Name:
Growth hormone releasing peptide
Synonyms
GHRP-6;GHRP-6 ACETATE;Growth;GROWTH HORMONE RELEASING PEPTIDE-6;gonadorel;Hexapeptide-2/GHRP-6;(2S)-6-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide;sk&f110679;HWAWFK-NH2;GHRP-6220vial
CBNumber:
CB8421540
Molecular Formula:
C46H56N12O6
Molecular Weight:
873.02
MDL Number:
MFCD00872694
MOL File:
87616-84-0.mol
MSDS File:
SDS
Last updated:2026-08-05 19:35:02
Product description Number Pack Size Price
[D-Trp7, Ala8, D-Phe10]-α-Melanocyte Stimulating Hormone Amide Fragment 6-11 ≥97% (HPLC) M2910 5mg $251
GHRP-6 PP50490 2mg $275
GHRP-6 PP50490 5mg $412.5
GHRP-6 PP50490 10mg $687.5
GHRP-6 PP50490 25mg $1031.25
More product size

Growth hormone releasing peptide Properties

Melting point >160o C (Dec.)
Boiling point 1407.0±65.0 °C(Predicted)
Density 1.333±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility Methanol (Slightly), Water (Slightly)
form Solid
pka 13.42±0.46(Predicted)
color White to Off-White
Sequence is-D-Trp-Ala-Trp-D-Phe-Lys-NH2|H-His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
Cosmetics Ingredients Functions SKIN CONDITIONING
InChIKey WZHKXNSOCOQYQX-FUAFALNISA-N
SMILES C(N)(=O)[C@H](CCCCN)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](C)NC(=O)[C@@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](CC1N=CNC=1)N
CAS DataBase Reference 87616-84-0(CAS DataBase Reference)
FDA UNII 4H7N4I6X6A

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3

Growth hormone releasing peptide price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M2910 [D-Trp7, Ala8, D-Phe10]-α-Melanocyte Stimulating Hormone Amide Fragment 6-11 ≥97% (HPLC) 87616-84-0 5mg $251 2026-04-30 Buy
Biosynth PP50490 GHRP-6 87616-84-0 2mg $275 2026-06-04 Buy
Biosynth PP50490 GHRP-6 87616-84-0 5mg $412.5 2026-06-04 Buy
Biosynth PP50490 GHRP-6 87616-84-0 10mg $687.5 2026-06-04 Buy
Biosynth PP50490 GHRP-6 87616-84-0 25mg $1031.25 2026-06-04 Buy
Product number Packaging Price Buy
M2910 5mg $251 Buy
PP50490 2mg $275 Buy
PP50490 5mg $412.5 Buy
PP50490 10mg $687.5 Buy
PP50490 25mg $1031.25 Buy

Growth hormone releasing peptide Chemical Properties,Uses,Production

Description

Growth hormone-releasing peptides (GHRPs) are synthetic, non-natural peptides endowed with potent stimulatory effects on somatotrope secretion in animals and humans. They have no structural homology with GHRH and act via specific receptors present either at the pituitary or the hypothalamic level both in animals and in humans.

Uses

L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide is a growth hormone releasing peptide.

Uses

Growth hormone releasing peptide-6 can promote the secretion of growth hormone, regulate food intake, increase weight, and promote animal growth.

benefits

When Growth hormone releasing peptide is administered, a selective pulse is sent to the brain that stimulates the hypothalamus and anterior pituitary to release growth hormones. Once this pulse is sent, the cells go directly to the muscle to support development while staying clear of any possible bone or cartilage growth. When the Peptide is injected it increases cell synthesis, elevates secretion levels of insulin from pancreatic tissue, and increases ghrelin in the stomach—which helps release GH and control hunger. All of these functions work to promote fat loss, shuttling of nutrients, and building clean muscle mass.

Biological Functions

Growth hormone releasing peptide (GHRH) is an endocrine hormone produced in the hypothalamus that acts on the receptors (GHRH-R) of the anterior pituitary gland to stimulate the release of growth hormone (GH).  GHRH includes GHRH-2 and GHRH-6, which have slightly different functions.  GHRH-2 is widely used to diagnose patients with growth hormone deficiency (GHD) and is believed to induce not only growth hormone (GH) release, but also adrenocorticotropic hormone (ACTH) release. GHRH-6 is part of a group of synthetic small peptides with potent growth hormone releasing activity, which has cellular and cardioprotective effects and can be used in heart disease treatment research.

Mechanism of action

Growth hormone releasing peptide is generally accepted that GHRPs stimulate the release of GH by acting at the level of the pituitary through a receptor different to that for the endogenous GH-releasing hormone (GHRH). In addition, it has been reported that there are specific binding sites for these peptides in the hypothalamus and that systemic administration of GHRPs increases the expression of the immediate early gene c-fos in a subpopulation of hypothalamic neurons.

Side effects

Carpal tunnel syndrome.Increased insulin resistance.
Type 2 diabetes.
Swelling in the arms and legs (edema)
Joint and muscle pain.
For men, enlargement of breast tissue (gynecomastia).
Increased risk of certain cancers.

Physiological effects

Growth hormone releasing peptide (GHRP) is a cyclase inhibitor that blocks the release of endogenous growth hormone.The peptide acts on both igf-i and somatotrophs, with receptor activity in the hypothalamus.GHRP can be used to increase body weight and control obesity.It has been shown to stimulate cell division and inhibit apoptosis in vitro.

Solubility in water

It is recommended to reconstitute the lyophilized growth hormone releasing peptide in sterile 18MΩ-cm H2O not less than 100 μg/ml, which can then be further diluted to other aqueous solutions.

storage

Lyophilized Growth hormone releasing peptide although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Growth hormone releasing peptide should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Background

GH-releasing peptides (GHRPs) are synthetic peptides that like GHRH act directly on pituitary somatotrophs to stimulate GH release. Growth hormone (GH) release is stimulated by a variety of synthetic secretagogues, of which growth hormone-releasing hexapeptide (GHRP-6) has been most thoroughly studied; it is thought to have actions at both pituitary and hypothalamic site.

Growth hormone releasing peptide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 302)Suppliers
Supplier Tel Email Country ProdList Advantage
Anko Intermational Trade Limited
+86-18073326374 sales@goodpeptides.com China 58 58
Forest chemical technology
+86-13854236000; +85295407470 grant@forestchem.freeqiye.com China 290 58
Hebei Jiafan Trading Company Limited
+86-15354498258; sales01@jiafan88.com China 207 58
Yiwu Fengjin Commercial Company
+86-19518257926 +86-19164429943 jaspercc0416@163.com China 998 58
Guangzhou XinPeptide International Co.,Ltd
18032808531 admin@xtpeptide.com China 191 58
BeiJing Beautide Co.,LTD
+852-852-62301937 +86-15591150975 graceskincare02@outlook.com China 139 58
Lotusland Life Sciences
+8615821988213 info@longyupharma.com China 2411 58
LIDE PHARMACEUTICALS LIMITED
+852-55945652 export@lidepharma.com China 302 58
Hangzhou ICH Biofarm Co., Ltd
+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 1002 58
Shandong Huisheng Import & Export Co., Ltd.
+86-13176845580 da@zhongda-biotech.com China 216 58

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GHRP-6 pictures 2026-08-14 GHRP-6
$1.00 1kit 99.9% 100KG .GZ HONESTCHEM CO.,LTD
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$1.00 1kit 99.9% 200 .GZ HONESTCHEM CO.,LTD
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D-TRP7,ALA8,D-PHE10]-A-MELANOCYTESTIMULATINGHORMONEAMIDEFRAGMENT6-11 (2S)-6-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(3H-imidazol-4-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]hexanamide Growth hormone releasing peptide (D-trp7,ala8,D-phe10)-A-melanocyte*stimulating ho (D-TRP7,ALA8,D-PHE10)-A-MELANOCYTE*STIMU LATING HORM [d-trp7, ala8, d-phe10]-α-melanocyte stimulating hormone amide fragment 6-11 Growth hormone-releasing peptide【synthetic】 L-His-D-Trp-L-Ala-L-Trp-D-Phe-L-Lys-NH2 [His1, Lys6] - GHRP, GHRP- 6 alpha-melanotropin, fragment 6-11, [D-Trp7,Ala8,D-Phe10] (D-Trp7,Ala8,D-Phe10)-a-MSH (6-11) aMide L-LysinaMide,L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl- (D-Trp7,Ala8,D-Phe10)-α-MSH (6-11) amide, GHRP-6 sk&f110679 [D-TRP7, ALA8, D-PHE10]-ALPHA-MELANOCYTE STIMULATING HORMONE (6-11) AMIDE [D-TRP7,ALA8,D-PHE10]-ALPHA-MELANOCYTE STIMULATING HORMONE FRAGMENT 6-11 AMIDE (D-TRP7,ALA8,D-PHE10)-ALPHA-MSH (6-11) AMIDE [HIS1, LYS6]-GHRP HIS-D-TRP-ALA-TRP-D-PHE-LYS-NH2 H-HIS-D-TRP-ALA-TRP-D-PHE-LYS-NH2 GROWTH HORMONE RELEASING PROTEIN-6 HWAWFK-NH2 (S)-6-Amino-2-((2R,5S,8S,11R,14S)-5,11-bis((1H-indol-3-yl)methyl)-14-amino-2-benzyl-15-(1H-imi High Purity Ghrp-6 Peptide For Lean Muscle Mass CAS NO.87616-84-0 CAS NO.87616-84-0 L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide GHRP-6220vial GHRP-6220vial(5mg/vial) GHRP-6(Growth hormone releasing peptide) L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide Acetate Salt GHRP-6 powder GH-Releasing peptide Pharmaceutical Grade Peptides Myostatin Gdf8 for Bodybuilding Peptide Powder Ghrp-6 Ghrp 6 for Injection Growth hormone releasing peptide USP/EP/BP (D-Trp7,Ala8,D-Phe10)-α-MSH (6-11) amide Peptides G-H-′ R-′ P-6 GRHP-6 Acetate GHRP-6 acetate salt (D-Trp?,Ala?,D-Phe??)-α-MSH (6-11) amide GHRP-6 Acetate/Hexapeptide-2/Growth hormone releasing peptide/ GHRP-6/Hexapeptide-2 [His1, Lys6]-Growth Hormone Releasing Peptide GHRP-6/5mg/10mg (2S)-6-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide gonadorel GHRP-6 ACETATE GHRP-6 Growth GROWTH HORMONE RELEASING PEPTIDE-6 Hexapeptide-2/GHRP-6 GHRP-6 Acetate G65 GHRP-6 Acetate G610 87616-84-0 102989-47-3 C50H64N12O6 BioChemical Cell Signaling and Neuroscience Cell Biology