Anti-Histone Deacetylase 5 (HDAC5) antibody, Mouse monoclonal

CAS No.
Chemical Name:
Anti-Histone Deacetylase 5 (HDAC5) antibody, Mouse monoclonal
Synonyms
Anti-Histone Deacetylase 5 (HDAC5) antibody, Mouse monoclonal
CBNumber:
CB84669298
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

Anti-Histone Deacetylase 5 (HDAC5) antibody, Mouse monoclonal Properties

storage temp. -20°C
form buffered aqueous solution

Anti-Histone Deacetylase 5 (HDAC5) antibody, Mouse monoclonal price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H4538 Anti-Histone Deacetylase 5 (HDAC5) antibody, Mouse monoclonal clone HDAC5-35, purified from hybridoma cell culture 200μL $608 2024-03-01 Buy
Product number Packaging Price Buy
H4538 200μL $608 Buy

Anti-Histone Deacetylase 5 (HDAC5) antibody, Mouse monoclonal Chemical Properties,Uses,Production

Uses

Anti-Histone Deacetylase 5 (HDAC5) antibody, Mouse monoclonal has been used in:

  • western blotting
  • immunostaining
  • enzyme-linked immunosorbent assay (ELISA)
  • immunocytochemistry
  • immunoprecipitation

General Description

Monoclonal Anti-Histone Deacetylase 5 (HDAC5) (mouse IgG1 isotype) is derived from the HDAC5-35 hybridoma produced by the fusion of mouse myeloma cells (NS1) and splenocytes from BALB/c mice immunized with a synthetic peptide. Mammalian HDACs can be divided into three classes according to sequence homology. Class II consists of the yeast Hda1-like proteins HDAC4, HDAC5, HDAC6, HDAC7, HDAC9 and HDAC10. Histone deacetylase 5 (HDAC5) is a histone deacetylase, located on human chromosome 17q21.

Biochem/physiol Actions

Histone deacetylase 5 (HDAC5) promotes progression of the cell cycle, cell proliferation and apoptosis. HDAC5 activity is important for the differentiation of muscle cells by binding, through its N-terminal domain, to the myocyte enhancer factor-2 (Mef2) protein, thus repressing expression of MEF2 downstream genes. Overexpression of HDAC5 in different cancer cells suppresses their growth by induction of apoptosis in a p53-independent manner. Reduced expression of the protein is observed in colon cancer and acute myeloid leukemia.

Anti-Histone Deacetylase 5 (HDAC5) antibody, Mouse monoclonal Preparation Products And Raw materials

Raw materials

Preparation Products

Anti-Histone Deacetylase 5 (HDAC5) antibody, Mouse monoclonal Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
Anti-Histone Deacetylase 5 (HDAC5) antibody, Mouse monoclonal