ST3932
- CAS No.
- 1246018-21-2
- Chemical Name:
- ST3932
- Synonyms
- ST3932;ST-3932,ST3932;9H-Purine-2-propanol, 6-amino-α,9-dimethyl-8-(2H-1,2,3-triazol-2-yl)-
- CBNumber:
- CB84805795
- Molecular Formula:
- C12H16N8O
- Molecular Weight:
- 288.32
- MDL Number:
- MFCD31746893
- MOL File:
- 1246018-21-2.mol
ST3932 Chemical Properties,Uses,Production
Description
ST3932 is a metabolite of ST1535, acts as an antagonist of adenosine A2A receptor, with Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively.
ST3932 is a metabolite of ST1535, acts as an antagonist of adenosine A2A receptor, with Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively. ST3932 inhibits agonist-induced cAMP accumulation with an IC50 value of 450 nM[1].
ST3932 (10, 20, 40 mg/kg, p.o.) antagonizes haloperidol-induced catalepsy, and increases motor activity in mice. ST3932 (20, 40 mg/kg, i.p.) significantly increases the number of contralateral turns induced by l-DOPA in rats[1].
References
[1]. ST3932, et al. Animal models of Parkinson?s disease: Effects of two adenosine A2A receptor antagonists ST4206 and ST3932, metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535). Eur J Pharmacol. 2015 Aug 15;761:353-61.
ST3932 Preparation Products And Raw materials
Raw materials
Preparation Products
ST3932 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Twochem Co.Ltd. | 021-58111628 15800915896 | China | 1988 | 58 | |
Tianjin Kaifu Pharmaceutical Technology Co., Ltd. | 18081075745 | chemflowtech@sina.com | China | 1886 | 58 |
DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 9946 | 58 |
TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
Twochem Co.Ltd. | 58 |
Tianjin Kaifu Pharmaceutical Technology Co., Ltd. | 58 |
DC Chemicals | 58 |
cjbscvictory | 58 |
TargetMol Chemicals Inc. | 58 |