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ST3932

CAS No.
1246018-21-2
Chemical Name:
ST3932
Synonyms
ST3932;ST-3932,ST3932;9H-Purine-2-propanol, 6-amino-α,9-dimethyl-8-(2H-1,2,3-triazol-2-yl)-
CBNumber:
CB84805795
Molecular Formula:
C12H16N8O
Molecular Weight:
288.32
MDL Number:
MFCD31746893
MOL File:
1246018-21-2.mol
Last updated:2023-05-21 10:59:17

ST3932 Properties

Boiling point 482.7±55.0 °C(Predicted)
Density 1.62±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 14.96±0.20(Predicted)

ST3932 Chemical Properties,Uses,Production

Description

ST3932 is a metabolite of ST1535, acts as an antagonist of adenosine A2A receptor, with Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively.

ST3932 is a metabolite of ST1535, acts as an antagonist of adenosine A2A receptor, with Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively. ST3932 inhibits agonist-induced cAMP accumulation with an IC50 value of 450 nM[1].

ST3932 (10, 20, 40 mg/kg, p.o.) antagonizes haloperidol-induced catalepsy, and increases motor activity in mice. ST3932 (20, 40 mg/kg, i.p.) significantly increases the number of contralateral turns induced by l-DOPA in rats[1].

References

[1]. ST3932, et al. Animal models of Parkinson?s disease: Effects of two adenosine A2A receptor antagonists ST4206 and ST3932, metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535). Eur J Pharmacol. 2015 Aug 15;761:353-61.

ST3932 Preparation Products And Raw materials

ST3932 Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Twochem Co.Ltd. 021-58111628 15800915896 China 1988 58
Tianjin Kaifu Pharmaceutical Technology Co., Ltd. 18081075745 chemflowtech@sina.com China 1886 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
cjbscvictory 13348960310 13348960310 3003867561@qq.com China 9946 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24131 58
ST3932 ST-3932,ST3932 9H-Purine-2-propanol, 6-amino-α,9-dimethyl-8-(2H-1,2,3-triazol-2-yl)- 1246018-21-2