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ChemicalBook >> CAS DataBase List >>L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Structure
L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- structure
CAS No.
2172819-77-9
Chemical Name:
L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
Synonyms
VH032-C7-COOH;VH 032 amide-alkylC8-acid;(S, R, S)-AHPC-nanoly-acid;L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;10-[[(S)-1-[(2S,4R)-4-Hydroxy-2-[[4-(4-methylthiazol-5-yl)benzyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxo-2-butyl]amino]-10-oxodecanoic Acid;10-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-10-oxodecanoic acid;9-{[(2S)-1-[(2S,4R)-4-hydroxy-2-({[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}carbamoyl)pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl}nonanoic acid
CBNumber:
CB88344467
Molecular Formula:
C32H46N4O6S
Molecular Weight:
614.8
MDL Number:
MFCD32898801
MOL File:
2172819-77-9.mol
Last updated:2025-08-21 22:16:43
Product description Number Pack Size Price
VH032amide-alkylC8-acid ≥95%(HPLC) 7108 25 $173
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L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Properties

Boiling point 892.3±65.0 °C(Predicted)
Density 1.217±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
pka 4.78±0.10(Predicted)

L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 7108 VH032amide-alkylC8-acid ≥95%(HPLC) 2172819-77-9 25 $173 2021-12-16 Buy
Product number Packaging Price Buy
7108 25 $173 Buy

L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Chemical Properties,Uses,Production

Description

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus alkylC8 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Uses

VH032-C7-COOH is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. VH032-C7-COOH contains an E3 ligase ligand and an alkyl linker with a terminal amine for conjugation of target protein ligands[1].

storage

Store at -20°C

References

[1] Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. WO2018106870A1.2018-06-14.

L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Preparation Products And Raw materials

Raw materials

Preparation Products

L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 6112 65
ChemShuttle, Inc. 0510-83588313-811 18800520310 sales@chemshuttle.com China 2999 62
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 71826 60
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1615 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62320 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1248 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24961 58
Henan Alpha Chemical Co., Ltd. 0371-55013243 15324716602 2853979810@qq.com China 9992 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
Daicel Chiral Technologies (China)CO.,LTD 65
ChemShuttle, Inc. 62
Shanghai YuanYe Biotechnology Co., Ltd. 60
Jilin Province Woda Biotechnology Co., Ltd. 58
Bide Pharmatech Ltd. 58
Beijing Biocreative Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Henan Alpha Chemical Co., Ltd. 58

View Lastest Price from L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
VH 032 amide-alkylC8-acid pictures 2025-08-21 VH 032 amide-alkylC8-acid
2172819-77-9
 US $748.00 / mg 10g TargetMol Chemicals Inc.
L-Prolinamide, N-(9-carboxy-1-oxononyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- VH 032 amide-alkylC8-acid 10-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-10-oxodecanoic acid (S, R, S)-AHPC-nanoly-acid VH032-C7-COOH 9-{[(2S)-1-[(2S,4R)-4-hydroxy-2-({[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}carbamoyl)pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamoyl}nonanoic acid 10-[[(S)-1-[(2S,4R)-4-Hydroxy-2-[[4-(4-methylthiazol-5-yl)benzyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxo-2-butyl]amino]-10-oxodecanoic Acid 2172819-77-9 C32H46N4O6S