Enasidenib

CAS No.
2095569-76-7
Chemical Name:
Enasidenib
Synonyms
2H6]-Enasidenib
CBNumber:
CB89310960
Molecular Formula:
C19H17F6N7O
Molecular Weight:
473.38
MDL Number:
MOL File:
2095569-76-7.mol
Last updated:2025-04-18 09:52:57

Enasidenib Chemical Properties,Uses,Production

Uses

Enasidenib-d6 (AG-221-d6) is the deuterium labeled Enasidenib (HY-18690)[1]. Enasidenib is an oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes, with IC50s of 100 and 400 nM against IDH2R140Q and IDH2R172K, respectively[2].

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110

Enasidenib Preparation Products And Raw materials

Raw materials

Preparation Products

Enasidenib Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Beiwanta Biotechnology Co., Ltd. 021-67187366 19901745723 info@bwtlab.com China 9648 58
Nanjing Shizhou Biology Technology Co.,Ltd 17301488900 judy.xia@synzest.com China 12582 58
2H6]-Enasidenib 2095569-76-7