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YM-49598
- CAS No.
- 738575-62-7
- Chemical Name:
- YM-49598
- Synonyms
- YM49598;YM-49598;YM 49598
- CBNumber:
- CB911075621
- Molecular Formula:
- C36H45Cl2N2O2+
- Molecular Weight:
- 608.67
- MDL Number:
- MOL File:
- 738575-62-7.mol
Last updated:2023-03-31 09:12:58
YM-49598 Chemical Properties,Uses,Production
Description
YM49598 is a novel non-peptide tachykinin receptor antagonist. YM49598 exhibited high binding affinities at NK(2) (pK(i) = 9.94 +/- 0.03) and NK(1) (pK(i) = 9.09 +/- 0.02) receptors, respectively. YM-49598 was almost inactive but produced a potent inhibition (IC(50) = 11 +/- 7 microg x kg(-1)) of the contraction of the rat urinary bladder induced by challenge with the NK(1)-selective receptor agonist [Sar9,Met(O(2))11]substance P sulphone (0.3 microg x kg(-1)).
YM-49598 Preparation Products And Raw materials
Raw materials
Preparation Products
YM-49598 Suppliers
Global( 2)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
YM 49598
YM49598
YM-49598
738575-62-7