ChemicalBook >> CAS DataBase List >>(6-{2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
(6-{2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
- CAS No.
- 265989-40-0
- Chemical Name:
- (6-{2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
- Synonyms
- 2-Hydroxy Atorvastatin Acetonide tert-Butyl Ester;(6-{2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester;(4R,6R)-6-[2-[2-(4-Fluorophenyl)-4-[[(2-hydroxyphenyl)aMino]carbonyl]-5-(1-Methylethyl)-3-phenyl-1H-pyrrol-1-yl]ethyl]-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester;1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-4-[[(2-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-
- CBNumber:
- CB91175351
- Molecular Formula:
- C40H47FN2O6
- Molecular Weight:
- 670.81
- MDL Number:
- MFCD07369404
- MOL File:
- 265989-40-0.mol
Last updated:2023-05-05 08:29:07
(6-{2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester Properties
Boiling point | 694.8±55.0 °C(Predicted) |
---|---|
Density | 1.18±0.1 g/cm3(Predicted) |
solubility | Acetone, Chloroform, Dichloromethane, Ethyl Acetate |
pka | 9.33±0.35(Predicted) |
form | Solid |
color | White Foamy |
(6-{2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | F595715 | 2-HydroxyAtorvastatinAcetonidetert-ButylEster | 265989-40-0 | 2mg | $85 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | HCH0069081 | (6-(2-(2-(4-FLUORO-PHENYL)-4-(2-HYDROXY-PHENYLCARBAMOYL)-5-ISOPROPYL-3-PHENYL-PYRROL-1-YL)-ETHYL)-2,2-DIMETHYL-(1,3)-DIOXANE-4-YL)-ACETIC ACID, TERT-BUTYL ESTER 95.00% | 265989-40-0 | 1MG | $739.2 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | HCH0069081 | (6-(2-(2-(4-FLUORO-PHENYL)-4-(2-HYDROXY-PHENYLCARBAMOYL)-5-ISOPROPYL-3-PHENYL-PYRROL-1-YL)-ETHYL)-2,2-DIMETHYL-(1,3)-DIOXANE-4-YL)-ACETIC ACID, TERT-BUTYL ESTER 95.00% | 265989-40-0 | 100MG | $2055.9 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 65015 | 2-HydroxyAtorvastatinAcetonidetert-ButylEster | 265989-40-0 | 50mg | $2120 | 2021-12-16 | Buy |
(6-{2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester Chemical Properties,Uses,Production
Chemical Properties
White Foamy Solid
Uses
A intermediate of the metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
Uses
An intermediate of the metabolite of Atorvastin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
Synthesis of (6-{2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester from 2-BENZYLOXYANILINE
(6-{2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester Preparation Products And Raw materials
(6-{2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester Suppliers
Global( 8)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 56086 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
(6-{2-[2-(4-Fluoro-phenyl)-4-(2-hydroxy-phenylcarbamoyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-2,2-dimethyl-[1,3]-dioxane-4-yl)-acetic Acid, tert-Butyl Ester
(4R,6R)-6-[2-[2-(4-Fluorophenyl)-4-[[(2-hydroxyphenyl)aMino]carbonyl]-5-(1-Methylethyl)-3-phenyl-1H-pyrrol-1-yl]ethyl]-2,2-diMethyl-1,3-dioxane-4-acetic Acid 1,1-DiMethylethyl Ester
2-Hydroxy Atorvastatin Acetonide tert-Butyl Ester
1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-4-[[(2-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-
265989-40-0
Intermediates