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ChemicalBook >> CAS DataBase List >>Pentanoic acid, 4-[[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-5-[[(2-pyrimidinylmethyl)amino]carbonyl]-2-pyrimidinyl]amino]-5-hydroxy-

Pentanoic acid, 4-[[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-5-[[(2-pyrimidinylmethyl)amino]carbonyl]-2-pyrimidinyl]amino]-5-hydroxy-

Pentanoic acid, 4-[[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-5-[[(2-pyrimidinylmethyl)amino]carbonyl]-2-pyrimidinyl]amino]-5-hydroxy- Structure
Pentanoic acid, 4-[[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-5-[[(2-pyrimidinylmethyl)amino]carbonyl]-2-pyrimidinyl]amino]-5-hydroxy- structure
CAS No.
2748151-94-0
Chemical Name:
Pentanoic acid, 4-[[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-5-[[(2-pyrimidinylmethyl)amino]carbonyl]-2-pyrimidinyl]amino]-5-hydroxy-
Synonyms
Pentanoic acid, 4-[[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-5-[[(2-pyrimidinylmethyl)amino]carbonyl]-2-pyrimidinyl]amino]-5-hydroxy-
CBNumber:
CB913203730
Molecular Formula:
C23H26ClN7O5
Molecular Weight:
515.95
MDL Number:
MOL File:
2748151-94-0.mol
Last updated:2023-05-25 10:22:58
Product description Number Pack Size Price
Avanafil metabolite M16 ≥95% 27844 1 mg $638
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Pentanoic acid, 4-[[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-5-[[(2-pyrimidinylmethyl)amino]carbonyl]-2-pyrimidinyl]amino]-5-hydroxy- Properties

Density 1.443±0.06 g/cm3(Predicted)
solubility DMSO: soluble
pka 4.54±0.10(Predicted)
form A solid

Pentanoic acid, 4-[[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-5-[[(2-pyrimidinylmethyl)amino]carbonyl]-2-pyrimidinyl]amino]-5-hydroxy- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27844 Avanafil metabolite M16 ≥95% 2748151-94-0 1 mg $638 2024-03-01 Buy
Product number Packaging Price Buy
27844 1 mg $638 Buy

Pentanoic acid, 4-[[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-5-[[(2-pyrimidinylmethyl)amino]carbonyl]-2-pyrimidinyl]amino]-5-hydroxy- Chemical Properties,Uses,Production

Description

Avanafil metabolite M16 is a major inactive metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil .1 Avanafil is metabolized by the cytochrome P450 (CYP450) isoforms CYP3A4 and CYP2C to the major metabolites avanafil metabolite M16 and avanafil metabolite M4 , as well as minor metabolites.2

References

1. Kedia, G.T., ückert, S., Assadi-Pour, F., et al. Avanafil for the treatment of erectile dysfunction: Initial data and clinical key properties Ther. Adv. Urol. 5(1),35-41(2013).
2. Kyle, J.A., Brown, D.A., and Hill, J.K. Avanafil for erectile dysfunction Ann. Pharmacother. 47(10),1312-1320(2013).

Pentanoic acid, 4-[[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-5-[[(2-pyrimidinylmethyl)amino]carbonyl]-2-pyrimidinyl]amino]-5-hydroxy- Preparation Products And Raw materials

Raw materials

Preparation Products

Pentanoic acid, 4-[[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-5-[[(2-pyrimidinylmethyl)amino]carbonyl]-2-pyrimidinyl]amino]-5-hydroxy- Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Cayman Chemical Company 800-364-9897 sales@caymanchem.com China 6838 58
Supplier Advantage
Shanghai Yifei Biotechnology Co. , Ltd. 58
Cayman Chemical Company 58
Pentanoic acid, 4-[[4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-5-[[(2-pyrimidinylmethyl)amino]carbonyl]-2-pyrimidinyl]amino]-5-hydroxy- 2748151-94-0 C23H26ClN7O5