dU(Deoxyuridine)phosphoramidite

Description

dU amidite enables the addition of deoxyuridine nucleoside to the DNA chain to synthesize modified oligonucleotides. Deoxyuridine (dU) is a derivative of the nucleoside uridine and has H instead of hydroxy group at the 2’-position of the ribose. This amidite contains DMT at the 5’-end.

Oligos modification with dU affects the melting profiles of oligo duplexes via integrating 2’-deoxyuridine into nucleic acid sequences.

dU (Deoxyuridine) phosphoramidite can serve for oligonucleotide probes and as a research tool for duplex stability studies and those of DNA damage and repair mechanisms.