Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate
![Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Structure](CAS/GIF/117337-19-6.gif)
- CAS No.
- 117337-19-6
- Chemical Name:
- Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate
- Synonyms
- kih-9201;Hsdb 7270;FLUTHIACET-METHYL;Eluthiacet-methyl;Semaglutide Impurity 9;Fluthiacet-methyl [iso];Fluthiacet-methyl Standard;Fluthiacet-methyl Solution;1000 μg/mL in Acetonitrile;fluthiacet-methyl (bsi, pa iso)
- CBNumber:
- CB9232165
- Molecular Formula:
- C15H15ClFN3O3S2
- Molecular Weight:
- 403.88
- MDL Number:
- MFCD03792701
- MOL File:
- 117337-19-6.mol
Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Properties
| Melting point | 104.6° |
|---|---|
| Boiling point | 503.5±60.0 °C(Predicted) |
| Density | 1.57±0.1 g/cm3(Predicted) |
| storage temp. | 0-6°C |
| pka | -2.86±0.20(Predicted) |
| BRN | 11510131 |
| FDA UNII | 7C989JK2XB |
| EPA Substance Registry System | Fluthiacet-methyl (117337-19-6) |
| Pesticides Freedom of Information Act (FOIA) | Fluthiacet-methyl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H400 |
| Precautionary statements | P273-P305+P351+P338 |
| Hazard Codes | Xi,N |
| Risk Statements | 36-50 |
| Safety Statements | 26-61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| HS Code | 29309090 |
| Toxicity | LD50 in rats (mg/kg): >5000 orally; >2000 dermally (Miyazawa) |
Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 32464 | Fluthiacet-methyl PESTANAL | 117337-19-6 | 25mg | $80.9 | 2022-05-15 | Buy |
| TRC | F599440 | Fluthiacet-methyl | 117337-19-6 | 5mg | $330 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | AGR0000191 | FLUTHIACET-METHYL 98.00% | 117337-19-6 | 0.5G | $1276 | 2021-12-16 | Buy |
| AHH | MT-51867 | Fluthiacet-methyl 98% | 117337-19-6 | 0.5g | $590 | 2021-12-16 | Buy |
Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Chemical Properties,Uses,Production
Uses
Herbicide.
Definition
ChEBI: Fluthiacet-methyl is a methyl ester resulting from the formal condensation of the carboxy group of fluthiacet with methanol. A proherbicide for fluthiacet, it is used for the control of broad-leaved weeds in crops such as maize and soya. It has a role as an agrochemical, an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor and a proherbicide. It is an organic sulfide, a methyl ester, a member of monochlorobenzenes, a member of monofluorobenzenes and a thiadiazolopyridazine. It is functionally related to a fluthiacet.
Metabolic pathway
Fluthiacet methyl is converted to its isomer, urazole, by
glutathione S-transferase (GST) and glutathione (GSH)
from some plants and rat liver microsomes. Fluthiacet
methyl inhibits Protox (protoporphyrinogen oxidase)
activity after conversion to the corresponding urazole by
GST and GSH. Fluthiacet methyl is chemically
converted to urazole with a thiol anion in media by the
nucleophilic reaction. It is also suggested that a free
acid of urazole, desulfated urazole, and the oxidative
ring-cleaved formyl degradation products result from
hydrolysis with esterase from soybean seedlings.
When fluthiacet methyl is administered orally to
rats in a single dose, 63-85% of the dose is excreted
in the feces and 10-23% in the urine, respectively,
after 48 h. The main metabolite is the isomer of
fluthiacet methyl (urazole) which is also identified in
the soil degradation products. Monohydroxylated
products on the pyridazine ring are identified as
metabolites by rats only.
Methyl 2-[2-chloro-4-fluoro-5-[(3-oxo-5,6,7,8-tetrahydro-[1,3,4]thiadiazolo[3,4-a]pyridazin-1-ylidene)amino]phenyl]sulfanylacetate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| XI'AN KPC-CN BIOLOGICAL TECHNOLOGY CO.,LTD. | 86-029-85456576 | daisy_wang@vip.163.com | China | 292 | 55 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4515 | 55 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20810 | 60 |
| Shandong Ono Chemical Co., Ltd. | 0539-6362799 20） | China | 9998 | 58 |