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C10-HOMOSERINE LACTONE

CAS No.
177315-87-6
Chemical Name:
C10-HOMOSERINE LACTONE
Synonyms
C10-HSL;C10-HOMOSERINE LACTONE;Decanoyl-L-hoMoserine lactone;N-DECANOYL-L-HOMOSERINE LACTONE;N-[(3S)-2-oxooxolan-3-yl]decanamide;C10-HSL, N-Decanoyl-L-hoMoserine lactone;(S)-N-(2-oxotetrahydrofuran-3-yl)decanamide;N-Decanoyl-L-homoserine lactone >=96% (HPLC);N-[(3S)-Tetrahydro-2-oxo-3-furanyl]decanamide;Decanamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-
CBNumber:
CB92456374
Molecular Formula:
C14H25NO3
Molecular Weight:
255.35
MDL Number:
MFCD11113140
MOL File:
177315-87-6.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:07

C10-HOMOSERINE LACTONE Properties

Melting point 127-130 °C
Boiling point 466.1±34.0 °C(Predicted)
Density 1.02±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 20 mg/ml
form A crystalline solid
pka 14.72±0.20(Predicted)
optical activity [α]/D -24±3°, c = 0.2 in methanol

SAFETY

Risk and Safety Statements

WGK Germany  3

C10-HOMOSERINE LACTONE price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 07028 N-Decanoyl-L-homoserine lactone ≥96% (HPLC) 177315-87-6 10mg $227 2024-03-01 Buy
Sigma-Aldrich 07028 N-Decanoyl-L-homoserine lactone ≥96% (HPLC) 177315-87-6 50mg $798 2023-06-20 Buy
Cayman Chemical 10011201 N-decanoyl-L-Homoserine lactone ≥96% 177315-87-6 5mg $44 2024-03-01 Buy
Cayman Chemical 10011201 N-decanoyl-L-Homoserine lactone ≥96% 177315-87-6 10mg $84 2024-03-01 Buy
Cayman Chemical 10011201 N-decanoyl-L-Homoserine lactone ≥96% 177315-87-6 25mg $193 2024-03-01 Buy
Product number Packaging Price Buy
07028 10mg $227 Buy
07028 50mg $798 Buy
10011201 5mg $44 Buy
10011201 10mg $84 Buy
10011201 25mg $193 Buy

C10-HOMOSERINE LACTONE Chemical Properties,Uses,Production

Uses

Decanoyl-L-homoserine lactone is an active quorum sensing modulator first recognised in Burkholderia pseudomallei. Decanoyl-L-homoserine lactone and other acylhomoserine lactones have been detected in hundreds of bacterial species and, while the homologues vary between species and strains, the homoserine lactones are the major chemical modulators of within and between cell communication and regulation. The most significant variable defining the function of the homoserine lactone is the length of the acyl chain, with shorter chains displaying opposing actions to the longer chains.

Definition

ChEBI: N-decanoyl-L-Homoserine lactone is a N-acyl-amino acid.

Biochem/physiol Actions

N-Decanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria; for reviews see. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs, and a research focus for the prevention of biofilm formation.

C10-HOMOSERINE LACTONE Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC Sciences
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N-DECANOYL-L-HOMOSERINE LACTONE C10-HSL, N-Decanoyl-L-hoMoserine lactone Decanoyl-L-hoMoserine lactone C10-HOMOSERINE LACTONE C10-HSL N-[(3S)-Tetrahydro-2-oxo-3-furanyl]decanamide N-[(3S)-2-oxooxolan-3-yl]decanamide Decanamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]- N-Decanoyl-L-homoserine lactone >=96% (HPLC) (S)-N-(2-oxotetrahydrofuran-3-yl)decanamide 177315-87-6