ChemicalBook >> CAS DataBase List >>Tubulysin A,TubA
Tubulysin A,TubA
- CAS No.
- 205304-86-5
- Chemical Name:
- Tubulysin A,TubA
- Synonyms
- TubA;CS-1324;Tubulysin A;Tubulysins A;Tubulysin A,TubA;(2S,4R)-4-[[2-[(1R,3R)-1-acetyloxy-4-methyl-3-[3-methylbutanoyloxymethyl-[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]amino]pentyl]-1,3-thiazole-4-carbonyl]amino]-5-(4-hydroxyphenyl)-2-methylpentanoicaci;Benzenepentanoic acid, γ-[[[2-[(1R,3R)-1-(acetyloxy)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl][(3-methyl-1-oxobutoxy)methyl]amino]pentyl]-4-thiazolyl]carbonyl]amino]-4-hydroxy-α-methyl-, (αS,γR)-
- CBNumber:
- CB92518395
- Molecular Formula:
- C43H65N5O10S
- Molecular Weight:
- 844.07
- MDL Number:
- MFCD12912448
- MOL File:
- 205304-86-5.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:20
| Melting point | 106-108 °C(Solv: methanol (67-56-1); water (7732-18-5)) |
|---|---|
| Boiling point | 979.9±65.0 °C(Predicted) |
| Density | 1.195±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | organic solvents: soluble |
| form | film |
| pka | 4.52±0.23(Predicted) |
| color | colorless or white |
| FDA UNII | X9RP3ADE9Z |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H311-H315-H319-H331-H335 |
| Precautionary statements | P261-P280-P301+P310-P305+P351+P338-P311 |
| Hazard Codes | T |
| Risk Statements | 23/24/25-36/37/38 |
| Safety Statements | 36/37-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
Tubulysin A,TubA price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | T897135 | TubulysinA | 205304-86-5 | 0.25mg | $385 | 2021-12-16 | Buy |
| TRC | T897135 | TubulysinA | 205304-86-5 | 1mg | $1405 | 2021-12-16 | Buy |
| TRC | T897135 | TubulysinA | 205304-86-5 | 2.5mg | $2805 | 2021-12-16 | Buy |
| TRC | T897135 | TubulysinA | 205304-86-5 | 5mg | $4235 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0004574 | TUBULYSIN A 95.00% | 205304-86-5 | 1MG | $2684.85 | 2021-12-16 | Buy |
Tubulysin A,TubA Chemical Properties,Uses,Production
Uses
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative.
Definition
ChEBI: Tubulysin A is a diester and a carboxylic acid.
Biochem/physiol Actions
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins are cytotoxic peptides, which include 9 members (A-I). Tubulysin A has potential application as an anticancer agent. It arrests cells in the G2/M phase. Tubulysin A inhibits polymerization more efficiently than vinblastine and induces depolymerization of isolated microtubules. Tubulysin A has potent cytostatic effects on various tumor cell lines with IC50 in the picomolar range.
Tubulysin A,TubA Preparation Products And Raw materials
Raw materials
Preparation Products
Tubulysin A,TubA Suppliers
Global( 48)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| ChemExpress | +86-021-58950125 | info@chemexpress.com | China | 557 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 | |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9440 | 58 |
View Lastest Price from Tubulysin A,TubA manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-26 | Tubulysin A,TubA
205304-86-5
|
US $1.00 / g | 1g | ≥98% | g/kg/Ton | Career Henan Chemical Co |
-
- Tubulysin A,TubA
205304-86-5
- US $1.00 / g
- ≥98%
- Career Henan Chemical Co
205304-86-5(Tubulysin A,TubA)Related Search:
TubA
Tubulysin A
Tubulysin A,TubA
Tubulysins A
CS-1324
Benzenepentanoic acid, γ-[[[2-[(1R,3R)-1-(acetyloxy)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl][(3-methyl-1-oxobutoxy)methyl]amino]pentyl]-4-thiazolyl]carbonyl]amino]-4-hydroxy-α-methyl-, (αS,γR)-
(2S,4R)-4-[[2-[(1R,3R)-1-acetyloxy-4-methyl-3-[3-methylbutanoyloxymethyl-[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]amino]pentyl]-1,3-thiazole-4-carbonyl]amino]-5-(4-hydroxyphenyl)-2-methylpentanoicaci
205304-86-5
C43H65N5O10S