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LeterMovir

LeterMovir structure

CAS No.: 917389-32-3

Chemical Name:: LeterMovir

Synonyms: Lettmove;AIC246;MK-8828;CS-2799;Letemovir;LeterMovir;Letermovlr;D3-Letermovir;LeterMovir-005;Letermovir (AIC246)

CBNumber:: CB92627305

Molecular Formula:: C29H28F4N4O4

Molecular Weight:: 572.55

MDL Number:: MFCD22572725

MOL File:: 917389-32-3.mol

MSDS File:: SDS

Last updated:2025-11-11 10:47:11

Product description	Number	Pack Size	Price
Letermovir ≥98% (HPLC)	SML3891	5 mg	$174.8
Letermovir ≥98% (HPLC)	SML3891	25 mg	$739
Letermovir ≥98%	17556	1mg	$73
Letermovir ≥98%	17556	5mg	$324
Letermovir ≥98%	17556	10mg	$502
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LeterMovir Properties

Boiling point	706.5±70.0 °C(Predicted)
Density	1.37±0.1 g/cm3(Predicted)
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	≥57.3 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form	solid
pka	4.00±0.10(Predicted)
color	Off-white to yellow
InChIKey	FWYSMLBETOMXAG-QHCPKHFHSA-N
SMILES	N1C2=C(C=CC=C2F)[C@H](CC(O)=O)N(C2=CC(C(F)(F)F)=CC=C2OC)C=1N1CCN(C2=CC=CC(OC)=C2)CC1
FDA UNII	1H09Y5WO1F
NCI Drug Dictionary	letermovir
ATC code	J05AX18
UNSPSC Code	12352200
NACRES	NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Warning
Hazard statements	H361-H373
Precautionary statements	P260-P314-P501-P201-P202-P281-P308+P313-P405-P501

LeterMovir price More Price(33)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML3891	Letermovir ≥98% (HPLC)	917389-32-3	5 mg	$174.8	2025-07-31	Buy
Sigma-Aldrich	SML3891	Letermovir ≥98% (HPLC)	917389-32-3	25 mg	$739	2025-07-31	Buy
Cayman Chemical	17556	Letermovir ≥98%	917389-32-3	1mg	$73	2024-03-01	Buy
Cayman Chemical	17556	Letermovir ≥98%	917389-32-3	5mg	$324	2024-03-01	Buy
Cayman Chemical	17556	Letermovir ≥98%	917389-32-3	10mg	$502	2024-03-01	Buy

Product number	Packaging	Price	Buy
SML3891	5 mg	$174.8	Buy
SML3891	25 mg	$739	Buy
17556	1mg	$73	Buy
17556	5mg	$324	Buy
17556	10mg	$502	Buy

LeterMovir Chemical Properties,Uses,Production

Uses

Letermovir acts as an orally or i.v administered cytomegalovirus terminus complex inhibitor, antiviral agent, used in the treatment of CMV infection which is prevalent in those with immunocompromised systems.

Biological Activity

Letermovir (AIC246) is an orally active, potent and selective human cytomegalovirus (HCMV) DNA terminase complex inhibitor th at blocks HCMV replication (EC50 = 0.9-3.1 nM among 17 clinial HCMV isolates; EC50 = 1.6-3.9 nM against 6 AD169-derived drug-resistant variants) by interfering with viral DNA cleavage/packaging. Letermovir exhibits little potency toward MCMV (Smith), RCMV (Maastricht), VZV (Oka), HSV-1 (166v VP22-GFP), HSV-2 (01-6332), HHV-6 (typeA-GS) or EBV (B95-8) (MCMV EC50 = 4.5 μM, all other EC50 >10 μM).

in vivo

Letermovir (10-100 mg/kg/day, p.o.) leads to a dose-dependent reduction of the HCMV titer in transplanted cells compared to that of the placebo-treated control group using the mouse xenograft model^[3].

LeterMovir synthesis

Synthesis of LeterMovir from Butanedioic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2S,3S)-, compd. with methyl (4S)-8-fluoro-3,4-dihydro-2-[4-(3-methoxyphenyl)-1-piperazinyl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4-quinazolineacetate (1:1)

LeterMovir Preparation Products And Raw materials

Raw materials

Preparation Products

LeterMovir Suppliers

Global( 262)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD	+86-576-88902229;+86-0576-88902229 +8613968687450	yuxin@yuxchem.com	China	167	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10237	58
HANGZHOU LEAP CHEM CO., LTD.	+86-571-87711850	market18@leapchem.com	China	43339	58
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
shandong perfect biotechnology co.ltd	+86-53169958659 +86-13153181156	sales@sdperfect.com	China	294	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8615965530500	nickzhang@hangyubiotech.com	China	5712	58
Hebei Xinsheng New Material Technology Co., LTD.	+86-16632316109	xinshengkeji@xsmaterial.com	China	1085	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
Hangzhou Hyper Chemicals Limited	+86-0086-57187702781 +8613675893055	info@hyper-chem.com	China	295	58
Strong peptide cross-border e-commerce Co. LTD	+undefined13930052870	qt01@qiangtaipharm.com	China	84	58

Supplier	Advantage
TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD	58
Hubei Ipure Biology Co., Ltd	58
HANGZHOU LEAP CHEM CO., LTD.	58
Hebei Yanxi Chemical Co., Ltd.	58
shandong perfect biotechnology co.ltd	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Hebei Xinsheng New Material Technology Co., LTD.	58
Anhui Ruihan Technology Co., Ltd	58
Hangzhou Hyper Chemicals Limited	58
Strong peptide cross-border e-commerce Co. LTD	58

Letermovir: Pharmacodynamics, Pharmacokinetics and Adverse Effects
Letermovir effectively inhibits cytomegalovirus, demonstrating high bioavailability, manageable pharmacokinetics, and tolerabl....
Nov 27，2024

View Lastest Price from LeterMovir manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	Letemovir 917389-32-3	US $0.00-0.00 / kg	1kg	99%	1000kg	Hebei Junhua Import and Export Co., LTD
2025-11-18	LeterMovir 917389-32-3	US $0.00-0.00 / kg	1kg	0.99	580kg	Wuhan Biocar Pharmacy CO.,Ltd.
2025-11-10	Letermovir 917389-32-3	US $80.00-297.00 / mg		99.85%	10g	TargetMol Chemicals Inc.

Letemovir
917389-32-3
US $0.00-0.00 / kg
99%
Hebei Junhua Import and Export Co., LTD

LeterMovir
917389-32-3
US $0.00-0.00 / kg
0.99
Wuhan Biocar Pharmacy CO.,Ltd.

Letermovir
917389-32-3
US $80.00-297.00 / mg
99.85%
TargetMol Chemicals Inc.

LeterMovir Spectrum

LeterMovir(917389-32-3)¹HNMR

917389-32-3(LeterMovir)Related Search:

2-Propenoic acid, 3-[3-fluoro-2-[[[[2-methoxy-5-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]-, methyl ester, (2E)- 2-Propenoic acid, 3-[3-fluoro-2-[[[4-(3-methoxyphenyl)-1-piperazinyl][[2-methoxy-5-(trifluoromethyl)phenyl]imino]methyl]amino]phenyl]-, methyl ester, (2E)- Bortezomib

AIC246 LeterMovir (4S)-8-Fluoro-3,4-dihydro-2-[4-(3-methoxyphenyl)-1-piperazinyl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4-quinazolineacetic acid 4-Quinazolineacetic acid, 8-fluoro-3,4-dihydro-2-[4-(3-methoxyphenyl)-1-piperazinyl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-, (4S)- AIC246;AIC 246;AIC-246 CS-2799 Letermovir (AIC246) MK-8828 LeterMovir-005 methyl(S)-2-(8-fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetate Letermovir-d6Q: What is Letermovir-d6 Q: What is the CAS Number of Letermovir-d6 LetermovirQ: What is Letermovir Q: What is the CAS Number of Letermovir Lettmove (S)-2-(8-Fluoro-3-(2-methoxy-5-(trifluoromethyl)phenyl)-2-(4-(3-methoxyphenyl)piperazin-1-yl)-3,4-dihydroquinazolin-4-yl)acetic acid Letermovlr LeterMovir Impurity 27 Cilnidipine Impurity 29 Letermovir, 10 mM in DMSO Letemovir (S)-{8-fluoro-2-[4-(3-methoxyphenyl)piperazine-1-yl]-3-(2-methoxy-5-trifluoromethylphenyl)-3,4-dihydroquinazoline-4-yl}acetic acid D3-Letermovir 917389-32-3 1616761-00-3 C29H28F4N4O4 API 917389-32-3