Rho Kinase Inhibitor V
- CAS No.
- 1072906-02-5
- Chemical Name:
- Rho Kinase Inhibitor V
- Synonyms
- Rho Kinase Inhibitor V;Rho Kinase Inhibitor V - CAS 1072906-02-5 - Calbiochem;1,4-Benzodioxin-2-carboxamide, 2,3-dihydro-N-[4-(1H-pyrazol-4-yl)phenyl]-
- CBNumber:
- CB92645099
- Molecular Formula:
- C18H15N3O3
- Molecular Weight:
- 321.33
- MDL Number:
- MFCD28138106
- MOL File:
- 1072906-02-5.mol
Last updated:2023-04-23 13:52:06
Rho Kinase Inhibitor V price More Price(1)
Rho Kinase Inhibitor V Chemical Properties,Uses,Production
General Description
A cell-permeable pyrazolyl carboxamide compound that acts as a potent, ATP-binding pocket-targeting inhibitor of ROCK-II (IC50 = 1.5 nM) and effectively inhibits the myosin light chain 2 phosphorylation on Thr18/Ser19 in A7r5 cells (IC50 = 72 nM). It afftects the activities of PKA, MRCK, Akt1 (IC50 = 0.186, 1.19, and 1.41 μM, respectively) and CYP-450 enzymes (% inhibition of 2C9/2D6/3A4/1A2 at 10 μM = 87/40/1/20, respectively) only at much higher concentrations.
Rho Kinase Inhibitor V Preparation Products And Raw materials
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Rho Kinase Inhibitor V Suppliers
Global( 15)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
VDM Biochemicals | 0330-2528181 | sales@vdmbio.com | United States | 510 | 64 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
---|---|
VDM Biochemicals | 64 |
Sigma-Aldrich | 80 |
Rho Kinase Inhibitor V
Rho Kinase Inhibitor V - CAS 1072906-02-5 - Calbiochem
1,4-Benzodioxin-2-carboxamide, 2,3-dihydro-N-[4-(1H-pyrazol-4-yl)phenyl]-
1072906-02-5