(2-BROMO-2-ETHYLBUTYRYL)UREA
- CAS No.
- 77-65-6
- Chemical Name:
- (2-BROMO-2-ETHYLBUTYRYL)UREA
- Synonyms
- Nictal;Adalin;Diacid;Hoggar;NYCTAL;URADAL;TILDIN;Fydalin;Kartryl;Nenesin
- CBNumber:
- CB9278578
- Molecular Formula:
- C7H13BrN2O2
- Molecular Weight:
- 237.09
- MDL Number:
- MFCD00047872
- MOL File:
- 77-65-6.mol
- MSDS File:
- SDS
Melting point | 116-119° |
---|---|
Density | 1.5528 (rough estimate) |
refractive index | 1.5140 (estimate) |
Water Solubility | 0.5g/L(20 ºC) |
Stability | Stable. Combustible. Incompatible with acids, alkalies, strong oxidizing agents. |
FDA UNII | 0Y299JY9V3 |
ATC code | N05CM04 |
EPA Substance Registry System | Carbromal (77-65-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P264-P270-P301+P312-P330-P501 |
Toxicity | LD50 oral in rat: 316mg/kg |
(2-BROMO-2-ETHYLBUTYRYL)UREA Chemical Properties,Uses,Production
Chemical Properties
white crystalline powder
Originator
Antineuralgiae,Jelfa
Definition
ChEBI: Carbromal is a N-acylurea.
Manufacturing Process
120 parts urea and 258 parts 2-bromo-2-ethylbutyrylbromide was mixed and stood at room temperature for 12 hours; then the mixture was heated about 3 hours on water bath and adjusted to alkaline pH with sodium bicarbonate after cooling. The unreacted products was dissolved in brine, the insoluble part was filtered off. The recrystallization from ethanol gave the title product - (2-bromo-2-ethyl-butyryl)urea as the colorless, odorless crystals. MP 114°- 118°C.
brand name
Adalin (Sterling Winthrop).
Therapeutic Function
Hypnotic, Sedative
General Description
Odorless tasteless white crystalline powder. Saturated solution in water neutral to litmus.
Air & Water Reactions
May be sensitive to prolonged exposure to air and light. Insoluble in water.
Reactivity Profile
The neat material may be sensitive to prolonged exposure to air and light. (2-BROMO-2-ETHYLBUTYRYL)UREA is incompatible with acids and alkalis.
Fire Hazard
Flash point data for (2-BROMO-2-ETHYLBUTYRYL)UREA are not available; however, (2-BROMO-2-ETHYLBUTYRYL)UREA is probably combustible.
Safety Profile
Poison by ingestion, subcutaneous, and possibly other routes. Moderately toxic via intravenous and intraperitoneal routes. Mutation data reported. A sedative, hypnotic, and central Intdious system depressant. When heated to decomposition it emits very toxic fumes of NOx and Br-.
(2-BROMO-2-ETHYLBUTYRYL)UREA Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
AFINE CHEMICALS LIMITED | +86-008657185134551 +86-18958018566 | sales@afinechem.com | China | 15394 | 58 |
Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | 1026@dideu.com | China | 8672 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
Ningbo jinuo chemical co., LTD | 0574-87314919 057487319282 | info@nbinno.com | China | 7028 | 58 |
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 15229059051 | 1027@dideu.com | China | 9977 | 58 |