MPBH (4-(4-N-Maleimidophenyl)butyric acid hydrazide hydrochloride + 1/2 dioxane)
- CAS No.
- Chemical Name:
- MPBH (4-(4-N-Maleimidophenyl)butyric acid hydrazide hydrochloride + 1/2 dioxane)
- Synonyms
- MPBH (4-(4-N-Maleimidophenyl)butyric acid hydrazide hydrochloride + 1/2 dioxane)
- CBNumber:
- CB93151261
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Last updated:2023-04-23 13:52:06
MPBH (4-(4-N-Maleimidophenyl)butyric acid hydrazide hydrochloride + 1/2 dioxane) Chemical Properties,Uses,Production
General Description
The MPBH is a heterobifunctional crosslinker containing sulfhydryl-reactive maleimide and carbonyl-reactive hydrazide moieties. Maleimides react with free sulfhydryls (-SH) to form stable thioether bonds. Hydrazide groups react with carbonyls (aldehydes and ketones) to form stable hydrazone bonds. Aldehyde groups can be created by periodate-oxidation of sialic acid and other sugar components of glycoprotein polysaccharides. Thus, MPBH is useful for conjugating glycoproteins and sulfhydryl-containing peptides or proteins. Alternatively, the hydrazide moiety can be reacted to carboxyl groups using the crosslinker EDC.
MPBH (4-(4-N-Maleimidophenyl)butyric acid hydrazide hydrochloride + 1/2 dioxane) Preparation Products And Raw materials
Raw materials
Preparation Products
MPBH (4-(4-N-Maleimidophenyl)butyric acid hydrazide hydrochloride + 1/2 dioxane) Suppliers
Global( 1)Suppliers
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Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
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Sigma-Aldrich | 80 |
MPBH (4-(4-N-Maleimidophenyl)butyric acid hydrazide hydrochloride + 1/2 dioxane)