ANTI-NF-KAPPA-B (P65)
- CAS No.
- Chemical Name:
- ANTI-NF-KAPPA-B (P65)
- Synonyms
- ANTI-P65;Anti-SytI;ANTI-RELA;Anti-NFKB3;Anti-SVP65;Anti-GOLPH5;Anti-GRASP65;Anti-FLJ23443;Anti-MGC131774;synaptotagmin I
- CBNumber:
- CB9328143
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00802848
- MOL File:
- Mol file
ANTI-NF-KAPPA-B (P65) price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4300543 | Anti-SYT1/SYT2 (Ab-202/199) antibody produced in rabbit affinity isolated antibody | 100μG | $441 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4300542 | Anti-SYT1 (Ab-309) antibody produced in rabbit affinity isolated antibody | 100μg | $441 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4300469 | Anti-RELA (Ab-529) antibody produced in rabbit affinity isolated antibody | 100μG | $441 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4300442 | Anti-RELA (Ab-505) antibody produced in rabbit affinity isolated antibody | 100μg | $441 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4300298 | Anti-RELA (Ab-536) antibody produced in rabbit affinity isolated antibody | 100μG | $441 | 2024-03-01 | Buy |
ANTI-NF-KAPPA-B (P65) Chemical Properties,Uses,Production
Biochem/physiol Actions
p65 is a subunit of the nuclear factor kappa-B, a second messenger, which activates the transcription of a number of genes in multiple tissues. The inhibitory effect of I-kappa-B upon NF-kappa-B in the cytoplasm is exerted primarily through the interaction with p65. p65 shows a weak DNA-binding site which could contribute directly to DNA binding in the NF-kappa-B complex. NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex. The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form of NFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NFKB complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1760 M62399.1 8-1767
ANTI-NF-KAPPA-B (P65) Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-NF-KAPPA-B (P65) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Yubo Biotechnology Co., Ltd. | -- | shybio@126.com | CHINA | 6969 | 58 |
| Beijing Luyuan Bird Biotechnology Co., Ltd. | -- | 15810802415@139.com | CHINA | 6757 | 58 |
| Beijing Dongge Boye Biotechnology Co., Ltd. | -- | 1861586486@qq.com | CHINA | 6652 | 58 |
| Shanghai Zeye Biotechnology Co., Ltd. | -- | shzeysw@163.com | CHINA | 6550 | 58 |
| Dongguan Biaobiao Experimental Equipment Technology Co., Ltd. | -- | CHINA | 6673 | 58 | |
| Shanghai Mengze Biotechnology Co., Ltd. | -- | luxionggang@126.com | CHINA | 6393 | 58 |
| Beijing Qiangxin Borui Biotechnology Co., Ltd. | -- | moumou@xxx.com | CHINA | 2992 | 58 |
| Guangzhou Dongrui Technology Co., Ltd. | -- | xiaoshan.wu@dr-tech.com.cn | CHINA | 2839 | 58 |
| Annuol (Beijing) Biotechnology Co., Ltd. | -- | inquiry@annoron.com | CHINA | 6434 | 58 |
| Beijing Xiangsheng Xingye Technology Co., Ltd. | -- | xs_bio@163.com | CHINA | 5130 | 58 |