ChemicalBook >> CAS DataBase List >>SRN-927)
SRN-927)
- CAS No.
- 1642297-01-5
- Chemical Name:
- SRN-927)
- Synonyms
- GDC-0927;SRN-927);GDC-0927 (RG-6047;(S)-2-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H-chromen-6-ol;2H-1-Benzopyran-6-ol, 2-[4-[2-[3-(fluoromethyl)-1-azetidinyl]ethoxy]phenyl]-3-(3-hydroxyphenyl)-4-methyl-, (2S)-
- CBNumber:
- CB93383848
- Molecular Formula:
- C28H28FNO4
- Molecular Weight:
- 461.53
- MDL Number:
- MFCD31631581
- MOL File:
- 1642297-01-5.mol
Last updated:2025-12-10 09:00:29
| Boiling point | 664.6±55.0 °C(Predicted) |
|---|---|
| Density | 1.257±0.06 g/cm3(Predicted) |
| pka | 9.83±0.10(Predicted) |
| form | Solid |
| color | Light yellow to yellow |
| FDA UNII | ST9B0EMC0H |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
SRN-927) Chemical Properties,Uses,Production
Uses
GDC-0927, is a novel, non-steroidal, and selective estrogen receptor antagonist.
in vivo
GDC-0927 is a novel, potent, non-steroidal, orally bioavailable, selective ER antagonist/ER degrader (SERD) that induces tumor regression in estrogen receptor (ER)+breast cancer (BC) patient-derived xenograft models[1].
SRN-927) Preparation Products And Raw materials
Raw materials
Preparation Products
SRN-927) Suppliers
Global( 20)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32435 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39035 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3506 | 58 |
| TaiChem Taizhou Limited | 052386810091 | zcwy9518@yeah.net | China | 3912 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5132 | 58 |
| ChemeGen | 18818260767 | 2625930290@qq.com | China | 6973 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59936 | 58 |
GDC-0927
2H-1-Benzopyran-6-ol, 2-[4-[2-[3-(fluoromethyl)-1-azetidinyl]ethoxy]phenyl]-3-(3-hydroxyphenyl)-4-methyl-, (2S)-
(S)-2-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H-chromen-6-ol
GDC-0927 (RG-6047
SRN-927)
1642297-01-5






