(+/-)-MUSCARINE CHLORIDE
- CAS No.
- 2936-25-6
- Chemical Name:
- (+/-)-MUSCARINE CHLORIDE
- Synonyms
- (+)-MUSCARINE;Muscarinic chloride;DL-MUSCARINCHLORIDE);DL-MUSCARINECHLORIDE;(+/-)-MUSCARINE CHLORIDE;(±)-Muscarine chloride hydrate;(+/-)-muscarine chloride approx. 95%;(+/-)-MUSCARINE CHLORIDE SYNTHETIC >99%;Tetrahydro-4α-hydroxy-N,N,N,5β-tetramethyl-2β-furanmethanaminium;[(4α-Hydroxy-5β-methyltetrahydrofuran-2β-yl)methyl]trimethylaminium
- CBNumber:
- CB9427721
- Molecular Formula:
- C9H20ClNO2
- Molecular Weight:
- 209.71
- MDL Number:
- MFCD00055067
- MOL File:
- 2936-25-6.mol
| storage temp. | room temp |
|---|---|
| solubility | deionized water: ≥20mg/mL |
| form | powder |
| color | white |
| FDA UNII | 7T101UWZ5W |
(+/-)-MUSCARINE CHLORIDE price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M104 | (±)-Muscarine chloride hydrate ≥98% (HPLC) | 2936-25-6 | 5mg | $167 | 2024-03-01 | Buy |
| Sigma-Aldrich | M104 | (±)-Muscarine chloride hydrate ≥98% (HPLC) | 2936-25-6 | 25mg | $537 | 2024-03-01 | Buy |
| TRC | M814005 | (+/-)-MuscarineChloride | 2936-25-6 | 25mg | $1175 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HBL0000023 | (+/-)-MUSCARINE CHLORIDE 95.00% | 2936-25-6 | 5MG | $578 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HBL0000023 | (+/-)-MUSCARINE CHLORIDE 95.00% | 2936-25-6 | 10MG | $883.49 | 2021-12-16 | Buy |
(+/-)-MUSCARINE CHLORIDE Chemical Properties,Uses,Production
Description
Muscarine is a natural alkaloid that is found in a number of wild mushrooms. Despite the fact that muscarine does not have any therapeutic value, it is of interest because of its expressed toxic properties, which made it one of the first systematically studied cholinomimetic substances. This compound was an underlying classification of cholinergic muscarinic receptors. The action of muscarine is similar to that of acetylcholine on peripheral autonomic effector organs, and atropine is an antagonist to it. Unlike acetylcholine, muscarine does not act on nicotinic receptors.
Uses
(+/-)-Muscarine Chloride is a muscarinic acteylcholine receptor agonist.
Biochem/physiol Actions
Muscarine is a potent agonist than acetylcholine and is not susceptible to degradation by cholinesterases. Muscarine administration results in muscle spasm especially in gut, bronchus and uterus.
Synthesis
Muscarine, 2-methyl-3-hydroxy-5-(N,N,N-trimethylammonium) methylentetrahydrofuran chloride (13.1.14), was first isolated from the poisonous mushrooms Amanita muscaria. It can be synthesized in various ways from completely different substances [16¨C24], particularly from 2,5-dimethyl-3-carboxymethylflurane, which undergoes a Curtius reaction, i.e. successive reactions with hydrazine and further with nitrous acid in isopropyl alcohol, which forms the urethane (13.1.9), the acidic hydrolysis of which gives 2,5-dimethyl-2H-furane-3 (13.1.10). Allylic bromination of this gives 2- methyl-5-bromomethyl-2H-furanone-3 (13.1.11), which is reacted with dimethylamine, forming 2-methyl-5-dimethylaminomethyl-2H-fluranone-3 (13.1.12). Reducing this compound leads to formation of 2-methyl-3-hydroxy-5-dimethylaminomethyltetrahydroflurane (13.1.13), the reaction of which with methyl chloride gives muscarine (13.1.14) as a mixture of stereoisomers.
(+/-)-MUSCARINE CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
(+/-)-MUSCARINE CHLORIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Moqi Biological Technology Co., LTD | 021-38218169 13341702378 | 190129269@qq.com | China | 9112 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24018 | 58 |
| Shandong Mopai Biotechnology Co., Ltd | 13053322091 13053322091 | admin@mopaikeji.com | China | 10974 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |