Anti-acetyl-Histone H3 (Ac-Lys9) antibody, Mouse monoclonal
- CAS No.
- Chemical Name:
- Anti-acetyl-Histone H3 (Ac-Lys9) antibody, Mouse monoclonal
- Synonyms
- Anti-acetyl-Histone H3 (Ac-Lys9) antibody, Mouse monoclonal
- CBNumber:
- CB94669008
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-acetyl-Histone H3 (Ac-Lys9) antibody, Mouse monoclonal price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | H0913 | Anti-acetyl-Histone H3 (Ac-Lys9) antibody, Mouse monoclonal clone AH3-120, purified from hybridoma cell culture | 25μL | $174 | 2024-03-01 | Buy | |
Sigma-Aldrich | H0913 | Anti-acetyl-Histone H3 (Ac-Lys9) antibody, Mouse monoclonal clone AH3-120, purified from hybridoma cell culture | 200μL | $713 | 2024-03-01 | Buy |
Anti-acetyl-Histone H3 (Ac-Lys9) antibody, Mouse monoclonal Chemical Properties,Uses,Production
Uses
Monoclonal Anti-acetyl-Histone H3 (Ac-Lys9) antibody may be used in various applications including ELISA, immunoblotting (approx. 17 kDa), and immunocytochemistry.
General Description
Monoclonal Anti-Acetyl-Histone H3 (Ac-Lys9) recognizes human histone H3 when acetylated on Lys9. Staining of the histone H3-Ac-Lys9 band in immunoblotting is specifically inhibited with the acetylated histone H3 immunizing peptide but not with the nonacetylated one.
Biochem/physiol Actions
Acetyl-Histone H3 hav Acetylation of lysine residues within these N-terminal domains of histones by histone acetyl-transferase (HATs), including Gcn5p, PCAF, p300/CBP and TAFII250 is associated with transcriptional activation. This modification results in remodeling of the nucleosome structure into an open conformation more accessible to transcription complexes. Conversely, histone deacetylation by histone deacetylase (HDACs) is associated with transcription repression reversing the chromatin remodeling process. In most species, histone H3 is primarily acetylated at lysine 9, 14, 18, and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Acetylation of specific lysines in histone H3 is also associated with processes apart from transcription. During DNA replication, new histones are rapidly synthesized and assembled into replicated DNA. Histones H3 and H4 are brought to replicating chromatin in a pre-acetylated state that turns into a de-acetylated state after replication is completed and the newly assembled chromatin matures.
Anti-acetyl-Histone H3 (Ac-Lys9) antibody, Mouse monoclonal Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-acetyl-Histone H3 (Ac-Lys9) antibody, Mouse monoclonal Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
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Sigma-Aldrich | 80 |