Anti-EEA1 antibody, Mouse monoclonal

CAS No.
Chemical Name:
Anti-EEA1 antibody, Mouse monoclonal
Synonyms
Anti-EEA1 antibody, Mouse monoclonal
CBNumber:
CB94669189
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

Anti-EEA1 antibody, Mouse monoclonal Properties

storage temp. -20°C
form buffered aqueous solution

Anti-EEA1 antibody, Mouse monoclonal price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E7659 Anti-EEA1 antibody, Mouse monoclonal clone EEA1-N19, purified from hybridoma cell culture 100μL $499 2024-03-01 Buy
Product number Packaging Price Buy
E7659 100μL $499 Buy

Anti-EEA1 antibody, Mouse monoclonal Chemical Properties,Uses,Production

Uses

Anti-EEA1 antibody, Mouse monoclonalhas been used in:

  • immunoblotting
  • immunoprecipitation
  • cell fractionation
  • indirect immunofluorescence
  • immunohistochemistry

General Description

Monoclonal Anti-EEA1 (mouse IgG2a isotype) is derived from the hybridoma EEA1-N19 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to a fragment of human EEA1. Early Endosome Antigen 1 (EEA1) is a dimer. It comprises extensive coiled-coil regions, and at its C-terminus contains a cysteine-rich zinc-finger-like domain named FYVE domain.

Biochem/physiol Actions

Early Endosome Antigen 1 (EEA1) FYVE domain is involved in intracellular trafficking and is implicated in the specific localization of EEA1 to endosomes . Endosomal targeting of EEA1 also requires its binding to the active form of the small GTPase Rabaptin-5 (Rab5). The binding of EEA1 to phosphatidylinositol 3-phosphate (PtdIns 3P) and Rab5-GTP is essential for the localization and function of EEA1 in endocytic membrane fusion. Monoclonal Anti-EEA1 may be used as an early endosome marker.

Anti-EEA1 antibody, Mouse monoclonal Preparation Products And Raw materials

Raw materials

Preparation Products

Anti-EEA1 antibody, Mouse monoclonal Suppliers

Global( 1)Suppliers
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
Sigma-Aldrich 80
Anti-EEA1 antibody, Mouse monoclonal