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CCG224406)

CCG224406) structure

CAS No.: 1870843-22-3

Chemical Name:: CCG224406)

Synonyms: CCG224406);CCG-224406 (CCG 224406;5-Pyrimidinecarboxamide, 4-[3-[[[(2,6-dimethoxyphenyl)methyl]amino]carbonyl]-4-fluorophenyl]-1,2,3,4-tetrahydro-N-1H-indazol-5-yl-6-methyl-2-oxo-

CBNumber:: CB94844621

Molecular Formula:: C29H27FN6O5

Molecular Weight:: 558.56

MDL Number:

MOL File:: 1870843-22-3.mol

Last updated:2023-03-31 09:12:57

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CCG224406) Properties

Boiling point	802.0±65.0 °C(Predicted)
Density	1.375±0.06 g/cm3(Predicted)
pka	11.09±0.70(Predicted)

CCG224406) Chemical Properties,Uses,Production

Description

CCG-22440 is a Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitor. CCG-224406 had an IC50 for GRK2 of 130 nM, greater than 700-fold selectivity over other GRK subfamilies, and no detectable inhibition of ROCK1. G protein-coupled receptors (GPCRs) are central to many physiological processes. Regulation of this superfamily of receptors is controlled by GPCR kinases (GRKs), some of which have been implicated in heart failure.

CCG224406) Preparation Products And Raw materials

Raw materials

Preparation Products

CCG224406) Suppliers

Global( 4)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	cindy.huang@synzest.com	China	12007	58

Supplier	Advantage
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
Nanjing Shizhou Biology Technology Co.,Ltd	58

CCG-224406 (CCG 224406 CCG224406) 5-Pyrimidinecarboxamide, 4-[3-[[[(2,6-dimethoxyphenyl)methyl]amino]carbonyl]-4-fluorophenyl]-1,2,3,4-tetrahydro-N-1H-indazol-5-yl-6-methyl-2-oxo- 1870843-22-3