Olean-12-en-28-oic acid, 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-xylopyranosyl]oxy]-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (3β)-
- CAS No.
- 140694-19-5
- Chemical Name:
- Olean-12-en-28-oic acid, 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-xylopyranosyl]oxy]-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (3β)-
- Synonyms
- Flaccidoside II;Olean-12-en-28-oic acid, 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-xylopyranosyl]oxy]-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (3β)-
- CBNumber:
- CB99780232
- Molecular Formula:
- C59H96O25
- Molecular Weight:
- 1205.39
- MDL Number:
- MOL File:
- 140694-19-5.mol
Olean-12-en-28-oic acid, 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-xylopyranosyl]oxy]-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (3β)- Chemical Properties,Uses,Production
Uses
Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell lines. Flaccidoside II ameliorates collagen-induced arthritis in mice. Flaccidoside II is an active triterpenoid saponin constituent from Anemone flaccida rhizome[1][2].
References
[1] Zhang GB, et al. Corrigendum to "Flaccidoside II ameliorates collagen-induced arthritis in mice" [Eur. J. Pharmacol. 880 (2020) 173155]. Eur J Pharmacol. 2021 Apr 15;897:173963. DOI:10.1016/j.ejphar.2021.173963
[2] Han LT, et al. Triterpenoid saponin flaccidoside II from Anemone flaccida triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors via the MAPK-HO-1 pathway. Onco Targets Ther. 2016 Apr 5;9:1969-79. DOI:10.2147/OTT.S95597
Olean-12-en-28-oic acid, 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-xylopyranosyl]oxy]-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (3β)- Preparation Products And Raw materials
Raw materials
Preparation Products
Olean-12-en-28-oic acid, 3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-xylopyranosyl]oxy]-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (3β)- Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3751 | 58 |
| Mensura Group Limited | 18780014153 | 1058503172@qq.com | China | 2900 | 58 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-028-85370565-229-229 18080489829 | 18080489829@163.com | China | 8247 | 60 |
| Shanghai Moqi Biological Technology Co., LTD | 021-38218169 13681877033 | 2702713455@qq.com | China | 9999 | 58 |
| Naturewill Biotechnology Co., Ltd. | 028-82632533 18113192475 | 3157321941@qq.com | China | 4993 | 58 |
| Shandong Mopai Biotechnology Co., Ltd | 13053322091 | admin@mopaikeji.com | China | 5830 | 58 |
| Mensura Group Limited | 17318633522 | 18109034517@163.com | China | 2898 | 58 |
| Hubei Danding Pharmaceutical Technology Co., Ltd | 17701422019 | 1559451077@qq.com | China | 8161 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 13308200041 | 2851167782@qq.com | China | 11146 | 58 |
| Chengdu DeSiTe Biological Technology Co., Ltd | 17308096051 | 3001048290@qq.com | China | 6219 | 58 |




