ZONIPORIDE
- CAS No.
- 241800-98-6
- Chemical Name:
- ZONIPORIDE
- Synonyms
- CP 597396;ZONIPORIDE;Zoniporide hydrochloride hydrate;[1-(quinolin-5-yl)-5-cycloPropyl-1H-pyrazole-4-formyl]guanidine;N-carbamimidoyl-5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxamide;N-[5-Cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carbonyl]guanidine;1H-Pyrazole-4-carboxamide, N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-;N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide hydrochloride hydrate
- CBNumber:
- CB02448312
- Molecular Formula:
- C17H16N6O
- Molecular Weight:
- 320.35
- MOL File:
- 241800-98-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2026/11/4 17:01:57
| Density | 1.54 |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: soluble2mg/mL, clear (warmed) |
| form | powder |
| pka | 11.44±0.46(Predicted) |
| color | white to tan |
| Water Solubility | H2O: 2mg/mL, clear (warmed) |
| InChI | 1S/C17H16N6O.ClH.H2O/c18-17(19)22-16(24)12-9-21-23(15(12)10-6-7-10)14-5-1-4-13-11(14)3-2-8-20-13;;/h1-5,8-10H,6-7H2,(H4,18,19,22,24);1H;1H2 |
| InChIKey | UCIJUEGJEFJRMP-UHFFFAOYSA-N |
| SMILES | O.Cl.NC(=N)NC(=O)c1cnn(-c2cccc3ncccc23)c1C4CC4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
ZONIPORIDE price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML0076 | Zoniporide hydrochloride hydrate ≥98% (HPLC) | 241800-98-6 | 10MG | ₹25590.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML0076 | Zoniporide hydrochloride hydrate ≥98% (HPLC) | 241800-98-6 | 50MG | ₹97316.75 | 2022-06-14 | Buy |
ZONIPORIDE Chemical Properties,Uses,Production
Uses
Zoniporide hydrochloride hydrate has been used for the inhibition of sodium-hydrogen exchanger isoform 1 (NHE-1) in rat models. It has also been used in cytotoxicity assay and to study its effect on lymphocytic choriomeningitis virus multiplication.
Biochem/physiol Actions
Zoniporide is a potent and selective inhibitor of Na+/H+ exchanger isoform 1 (NHE-1). IC50 = 59 nM at NHE-1, vs. 12,000 nM at NHE-2; Zoniporide inhibits NHE-1-dependent Na+ update with IC50 of 14 nM.
ZONIPORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
ZONIPORIDE Suppliers
Global( 35)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | China | 49898 | 58 | Inquiry | |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | United States | 32430 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-81148696 +86-15129568250 | China | 29083 | 58 | Inquiry |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | China | 39006 | 58 | Inquiry |
| Soochow Chirally Material Science and Technology Co.,Ltd | +86-51266834346 +86-17751128648 | China | 1050 | 58 | Inquiry |
| Shanghai Yaoheping Biopharmaceutical Technology Co., Ltd | 57540919 13120888836 | China | 9333 | 58 | Inquiry |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | China | 17234 | 58 | Inquiry |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | China | 9767 | 55 | Inquiry |
| Shanghai YuanYe Biotechnology Co., Ltd. | 18916372613 | China | 87240 | 60 | Inquiry |
| Zhengzhou Allchem Chemical Co., Ltd | 17734807184 17734807184 | China | 1315 | 58 | Inquiry |
241800-98-6(ZONIPORIDE)Related Search:
N-[5-Cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carbonyl]guanidine
CP 597396
ZONIPORIDE
N-(Aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-1H-pyrazole-4-carboxamide hydrochloride hydrate
Zoniporide hydrochloride hydrate
1H-Pyrazole-4-carboxamide, N-(aminoiminomethyl)-5-cyclopropyl-1-(5-quinolinyl)-
N-carbamimidoyl-5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxamide
[1-(quinolin-5-yl)-5-cycloPropyl-1H-pyrazole-4-formyl]guanidine
241800-98-6