ChemicalBook > Product Catalog >API >Antipyretic analgesics >Antipyretic analgesics >Chlorogenic acid
Chlorogenic acid
- CAS No.
- 327-97-9
- Chemical Name:
- Chlorogenic acid
- Synonyms
- CAFFEOYLQUINIC ACID;Heriguard;3-CAFFEOYLQUINIC ACID;3-O-CAFFEOYLQUINIC ACID;ISOCHLOROGENIC ACID;Chlorogenic;CHLOROGENIC ACIDS;CHLOROGENID ACID;(1R,3R,4S,5R)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxy-cyclohexane-1-carboxylic acid;Buthotoxin
- CBNumber:
- CB2478906
- Molecular Formula:
- C16H18O9
- Molecular Weight:
- 354.31
- MOL File:
- 327-97-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2026/4/29 10:17:26
| Melting point | 210 °C (dec.) (lit.) |
|---|---|
| alpha | -36 º (c=1, H2O) |
| Boiling point | 407.55°C (rough estimate) |
| Density | 1.3594 (rough estimate) |
| refractive index | -37 ° (C=1, H2O) |
| storage temp. | 2-8°C |
| solubility | Soluble in ethanol and acetone. |
| pka | 3.91±0.50(Predicted) |
| form | Powder, Crystals, Needles and/or Chunks |
| color | White to almost white |
| Water Solubility | SOLUBLE IN HOT WATER |
| Merck | 14,2142 |
| Cosmetics Ingredients Functions |
SKIN CONDITIONING ANTIOXIDANT SKIN PROTECTING |
| InChI | 1S/C16H18O9/c17-9-3-1-8(5-10(9)18)2-4-13(20)25-12-7-16(24,15(22)23)6-11(19)14(12)21/h1-5,11-12,14,17-19,21,24H,6-7H2,(H,22,23)/b4-2+/t11-,12-,14-,16+/m1/s1 |
| InChIKey | CWVRJTMFETXNAD-JUHZACGLSA-N |
| SMILES | O[C@@H]1C[C@](O)(C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@@H]1O)C(O)=O |
| LogP | -0.356 (est) |
| CAS DataBase Reference | 327-97-9(CAS DataBase Reference) |
| EPA Substance Registry System | Chlorogenic acid (327-97-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 68 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GU8480000 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29182900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Toxicity | LDLo intraperitoneal in rat: 4gm/kg | |||||||||
| NFPA 704 |
|
Chlorogenic acid price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C3878 | Chlorogenic acid ≥95% (titration) | 327-97-9 | 250MG | ₹2749.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C3878 | Chlorogenic acid ≥95% (titration) | 327-97-9 | 1G | ₹8281.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR2202 | Chlorogenic Acid Pharmaceutical Secondary Standard; Certified Reference Material | 327-97-9 | 100MG | ₹18380.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C3878 | Chlorogenic acid ≥95% (titration) | 327-97-9 | 5G | ₹31251.78 | 2022-06-14 | Buy |
| ALFA India | ALF-J60457-MD | Chlorogenic acid | 327-97-9 | 250mg | ₹2264 | 2022-05-26 | Buy |
Chlorogenic acid Chemical Properties,Uses,Production
Chemical Properties
white to slightly yellowish-beige powder
General Description
Chlorogenic acid is a bioactive polyphenolic compound mainly found in many plants, such as coffee. It is a potent neuroprotectant and also possesses antiviral, antifungal, antioxidant and antitumor properties. CGA may also be involved in regulating glucose and lipid metabolism and improving insulin sensitivity.
Anticancer Research
Chlorogenic acid plays a major role in the prevention and inhibition of tumor growth, and the anti-tumor mechanism can be summarized as follows: (1) Regulate the expression of apoptosis-related factors and promote apoptosis of cancer cells; (2) It acts on the cell division cycle and hinders the reproduction, metastasis, and invasion of cancer cells; (3) Affect the metabolism level of cancer cells and the normal growth of cancer cells[1].
Purification Methods
Crystallise the acid from water and dry it at 110o. [Beilstein 10 H 537, 10 I 271, 10 II 378, 10 III 2408, 10 IV 2259.]
References
[1] Wang, L., Pan, X., Jiang, L., Chu, Y., Gao, S., Jiang, X., Zhang, Y., Chen, Y., Luo, S., Peng, C. (2022). The Biological Activity Mechanism of Chlorogenic Acid and Its Applications in Food Industry: A Review. Frontiers in Nutrition, 943911. https://doi.org/10.3389/fnut.2022.943911
Chlorogenic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 880)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4535 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Mumbai, India | 66 | 58 | Inquiry |
| Vedzon Healthcare Pvt Ltd | +91-9322176000 | Maharashtra, India | 51 | 58 | Inquiry |
| Bioextract | +91-8042633900 +91-9620333000 | Karnataka, India | 19 | 58 | Inquiry |
| Dr. ASCRO Bio Sciences Private Limited | +undefined-7382260502 +undefined-+91 9182680914 | Telangana, India | 51 | 58 | Inquiry |
| AVIGYABIOSCIENCES PRIVATE LIMITED | +91-9849533087 | Telangana, India | 156 | 58 | Inquiry |
| Apollo ingredients Pvt Ltd | +91-7219888886 | Maharashtra, India | 31 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5870 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6905 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| Vedzon Healthcare Pvt Ltd | 58 |
| Bioextract | 58 |
| Dr. ASCRO Bio Sciences Private Limited | 58 |
| AVIGYABIOSCIENCES PRIVATE LIMITED | 58 |
| Apollo ingredients Pvt Ltd | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
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Related Qustion
- Q:What are the natural sources of chlorogenic acid?
- A:
- Apr 30，2026
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