β-Secretase Substrate IV, Fluorogenic - Calbiochem 化学特性,用途語,生産方法
一般的な説明
A highly sensitive fluorescence resonance energy transfer (FRET) peptide substrate (excitation max.: ~350 nm; emission max.: ~490), based on the GVNLDAEF sequence derived from the β-secretase site of the Swedish mutation of Amyloid Precursor Protein. Hydrolysis of the substrate at Leu-Asp bond by β-secretase results in fluorescence enhancement. Reported K
cat/k
m values (min
-1/μM) for pro-mempasin 2 and its proteolytically activated species Leu
28p-mempasin 2 are 0.044 and 0.040, respectively (at pH 4.5, 37°C).
Biochem/physiol Actions
Product does not compete with ATP.
β-Secretase Substrate IV, Fluorogenic - Calbiochem 上流と下流の製品情報
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