3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE

 化学構造式
562823-84-1
CAS番号.
562823-84-1
化学名:
别名:
英語名:
3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE
英語别名:
MDM2-IN-20;MDM2 Inhibitor;TRANS-4-IODO,4'-BORANYL-CHALCONE;MDM2 Inhibitor - CAS 562823-84-1 - Calbiochem;3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE;3-(4-IODO-PHENYL)-1-(4''- BORANYL-PHENYL)-PROP-2-ENONE (FOR R&D ONLY);Boronic acid, B-[4-[(2E)-3-(4-iodophenyl)-1-oxo-2-propen-1-yl]phenyl]-
CBNumber:
CB1219430
化学式:
C15H12BIO3
分子量:
377.97
MOL File:
562823-84-1.mol
MSDS File:
SDS

3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE 物理性質

貯蔵温度 :
+2C to +8C
溶解性:
DMSO: >30 mg/mL、可溶
外見 :
個体

安全性情報

WGK Germany  3

3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE 化学特性,用途語,生産方法

一般的な説明

A cell-permeable boranyl-chalcone compound that binds strongly to MDM2 and irreversibly disrupts MDM2/p53 protein complex formation. Exhibits selective toxicity to MDM2-overexpressing human breast cancer cell lines (IC50 = 10 μM for MDA-MB-435, 8.8 μM for MDA-MB-231, and 7 μM for Wt-MCF7) compared to normal breast cell lines (IC50 = 75 μM for MCF-10A and 63 μM for MCF-12A).

Biochem/physiol Actions

Cell permeable: yes

3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE 上流と下流の製品情報

原材料

準備製品


3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE 生産企業

Global( 16)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
Aladdin Scientific
+1-833-552-7181
sales@aladdinsci.com United States 52927 58
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725
malulu@leyan.com China 40041 58
Yantai Lianhua Technology Co., Ltd 15552437730
1701654643@qq.com China 11397 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826
market@aladdin-e.com China 48570 58

562823-84-1()キーワード:


  • 562823-84-1
  • 3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE
  • 3-(4-IODO-PHENYL)-1-(4''- BORANYL-PHENYL)-PROP-2-ENONE (FOR R&D ONLY)
  • TRANS-4-IODO,4'-BORANYL-CHALCONE
  • MDM2 Inhibitor
  • MDM2 Inhibitor - CAS 562823-84-1 - Calbiochem
  • Boronic acid, B-[4-[(2E)-3-(4-iodophenyl)-1-oxo-2-propen-1-yl]phenyl]-
  • MDM2-IN-20
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