ChemicalBook >제품 카탈로그 >3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE

3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE

3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE 구조식 이미지

카스 번호:: 562823-84-1

상품명:: 3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE

동의어(영문):: MDM2-IN-20;MDM2 Inhibitor;TRANS-4-IODO,4'-BORANYL-CHALCONE;MDM2 Inhibitor - CAS 562823-84-1 - Calbiochem;3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE;3-(4-IODO-PHENYL)-1-(4''- BORANYL-PHENYL)-PROP-2-ENONE (FOR R&D ONLY);Boronic acid, B-[4-[(2E)-3-(4-iodophenyl)-1-oxo-2-propen-1-yl]phenyl]-

CBNumber:: CB1219430

분자식:: C15H12BIO3

포뮬러 무게:: 377.97

MOL 파일:: 562823-84-1.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 16

3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE 속성

저장 조건: +2C to +8C

용해도: DMSO: >30mg/mL, 용해성

물리적 상태: 고체

물리적 상태: 단단한 모양

안전

WGK 독일	3

3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE C화학적 특성, 용도, 생산

일반 설명

A cell-permeable boranyl-chalcone compound that binds strongly to MDM2 and irreversibly disrupts MDM2/p53 protein complex formation. Exhibits selective toxicity to MDM2-overexpressing human breast cancer cell lines (IC₅₀ = 10 μM for MDA-MB-435, 8.8 μM for MDA-MB-231, and 7 μM for Wt-MCF7) compared to normal breast cell lines (IC₅₀ = 75 μM for MCF-10A and 63 μM for MCF-12A).

Biochem/physiol Actions

Cell permeable: yes

3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE 준비 용품 및 원자재

원자재

준비 용품

3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE 공급 업체

글로벌( 16)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Shanghai Haohong Scientific Co., Ltd.	400-400-8210725	malulu@leyan.com	China	40041	58
Yantai Lianhua Technology Co., Ltd	15552437730	1701654643@qq.com	China	11400	58
Shanghai Aladdin Biochemical Technology Co.,Ltd.	+86-18521732826	market@aladdin-e.com	China	48617	58

3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE 관련 검색:

3-(4-IODO-PHENYL)-1-(4'-BORANYL-PHENYL)-PROP-2-ENONE 4-Carboxyphenylboronic acid