C1Q

C1Q 化学構造式
80295-33-6
CAS番号.
80295-33-6
化学名:
C1Q
别名:
C1Q;補体成分C1Q ヒト血清由来
英語名:
C1Q, HUMAN
英語别名:
C1Q, HUMAN;COMPLEMENT 1Q;COMPLEMENT 1Q, HUMAN;COMPLEMENT C1Q, HUMAN;COMPLEMENT C1Q PROTEIN;COMPLEMENT COMPONENT C1Q;COMPLEMENT C1Q PROTEIN HUMAN;COMPLEMENT COMPONENT C1Q FROM HUMAN*SERUM;activity:18-30units/mgproteinsalt-free,lyophilizedsolidbysds
CBNumber:
CB2270821
化学式:
分子量:
0
MOL File:
Mol file

C1Q 物理性質

貯蔵温度 :
-70°C
外見 :
溶液 (10 mM HEPES、pH 7.2、および 0.3 M NaCl)

安全性情報

主な危険性  B
WGK Germany  3

C1Q 価格 もっと(3)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
Sigma-Aldrich Japan C1740 補体成分C1q ヒト血清由来 ≥95% (SDS-PAGE)
Complement component C1q from human serum ≥95% (SDS-PAGE)
80295-33-6 0.5mg ¥115000 2024-03-01 購入
Sigma-Aldrich Japan C1740 補体成分C1q ヒト血清由来 ≥95% (SDS-PAGE)
Complement component C1q from human serum ≥95% (SDS-PAGE)
80295-33-6 1mg ¥196000 2024-03-01 購入
Sigma-Aldrich Japan C1740 補体成分C1q ヒト血清由来 ≥95% (SDS-PAGE)
Complement component C1q from human serum ≥95% (SDS-PAGE)
80295-33-6 .5mg ¥84300 2018-12-25 購入

C1Q 化学特性,用途語,生産方法

使用

Complement component C1q is an important regulator factor for platelet activation. This has been a topic for research, as platelet-leukocyte aggregates play an important role in inflammatory conditions such as coronary heart disease. In particular, C1q has been shown to inhibit collagen induced aggregation and enhance production of reactive oxygen species (ROS).

一般的な説明

C1q, together with C1r and C1s, in the ratio of 1:2:2, form the C1 complex which is the first component of the classical complement pathway. C1q is composed of 18 polypeptide chains (six A, six B, six C) (MW 460 kDa). All contain an 81-aa collagen-like region composed of (Gly-Xaa-Yaa) repeating sequences close to the N-terminus. Three chains (A1B1C1) form a triple helix with the C-terminus forming the globular heads which may be structurally and functionally distinct domains.

Biochem/physiol Actions

≥150,000 C1qH50 units/mg and ≥70% C1q activity in normal human serum on a mg/mg basis

C1Q 上流と下流の製品情報

原材料

準備製品


C1Q 生産企業

Global( 30)Suppliers
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